… in situ single-pass intestinal perfusion method in rats for intestinal permeability investigation
… In this work, the predicted Fabs of metformin and ranitidine using above-mentioned equation …

… region-dependent permeability of metformin, using the rat single-pass intestinal perfusion
method (… The weight but also the disease burden have an impact on intestinal permeability and …

… intestinal permeability data. The rat single-pass intestinal perfusion (SPIP) and intestinal …
and evaluate all the available intestinal permeability data for drugs that have been obtained …

… Therefore, expecting that intestinal permeability is the major determinant … a single-pass
intestinal perfusion study in rats [33], P e f f , r a t was lower at a higher concentration of metformin …

… common rat perfusion techniques—(a) single-pass intestinal … red in samples from rat intestinal
permeability studies: HPLC … for simultaneous determination of metformin hydrochloride, …

… concentrations, enhancing intestinal permeability and oral … from rabbit intestine adopting a
single pass intestinal perfusion … In situ intestinal perfusion in rodents: Future perspectives for …

… intestinal perfusion studies using suitable animal models), in vitro permeation studies using
excised intestinal … monolayer and in vivo rat system was evaluated. It was reported that all …

… Single pass intestinal perfusion is one of the most common … PR in perfusion medium. The
developed method could be helpful for researchers working on in-situ rat intestinal permeability …

… knockout mice had significantly lower bioavailability of metformin … Caco-2 cell monolayers
and intestinal rat perfusion, … the intestinal permeability for some poorly permeable compounds …

… situ single-pass intestinal perfusion, oral bioavailability in rats, … this effect was comparable
with that of metformin [6,7]. Decades of … increases the intestinal permeability of BBR by 5.5-fold. …