Assessment of culture/preservation conditions of human islets for transplantation
Y Shindo, J Kalivarathan, PB Saravanan… - … Transplantation, 2022 - journals.sagepub.com
… or preservation of islets before transplantation is required to … effect of islet preservation on
viability and function of islets when … to identify optimal culture/preservation conditions that result …
viability and function of islets when … to identify optimal culture/preservation conditions that result …
Optimal Time to Ship Human Islets Post Tissue Culture to Maximize Islet Recovery
BJ Olack, M Alexander, CJ Swanson… - … Transplantation, 2020 - journals.sagepub.com
… In summary, we determined that an increased duration of 37C culture time for human islets
prior to overnight shipping may reduce islet loss experienced by investigator recipients. This …
prior to overnight shipping may reduce islet loss experienced by investigator recipients. This …
[HTML][HTML] Advances in pancreatic islet transplantation sites for the treatment of diabetes
F Cayabyab, LR Nih, E Yoshihara - Frontiers in endocrinology, 2021 - frontiersin.org
… days before the islet develops a functional vasculature (111), but even then, the transplanted
islets … In addition, islets transplanted in the epidermal fat site have lower, controlled glucose …
islets … In addition, islets transplanted in the epidermal fat site have lower, controlled glucose …
[HTML][HTML] Human islet isolation and distribution efforts for clinical and basic research
N Ng, WX Tan, Y Koh, A Teo - OBM Transplantation, 2019 - lidsen.com
… This review also highlights the value of human islets for clinical transplantation as well as
basic … Functional validation prior to clinical islet transplantation is presently not mandatory, but …
basic … Functional validation prior to clinical islet transplantation is presently not mandatory, but …
Semi-automated assessment of human islet viability predicts transplantation outcomes in a diabetic mouse model
M Salgado, N Gonzalez, L Medrano… - … transplantation, 2020 - journals.sagepub.com
… , Aliso Viejo, CA, USA) until they were distributed for analyses. … of isolated islets: islet
count (post-isolation islet equivalent … use of clinical islet transplantation data, before it can be …
count (post-isolation islet equivalent … use of clinical islet transplantation data, before it can be …
[HTML][HTML] The future of clinical islet transplantation in the United States
MF Knoll, CA Knoll, R Bottino, S Bertera… - OBM Transplantation, 2021 - lidsen.com
… been a world leader in autologous islet transplantation (Tx) (ie, … world in allogeneic islet Tx
(ie, islets from deceased human … for islet xenoTx remains problematic until allogeneic islet Tx …
(ie, islets from deceased human … for islet xenoTx remains problematic until allogeneic islet Tx …
Failure mode and effect analysis in human islet isolation: from the theoretical to the practical risk
Q Perrier, V Lavallard, N Pernin, CH Wassmer… - Islets, 2021 - Taylor & Francis
… islet transplantation procedure, including islet isolation technology, quality control, shipment
of islets … during culture medium changes or the harvesting of islets before transplantation. …
of islets … during culture medium changes or the harvesting of islets before transplantation. …
Bilirubin improves the quality and function of hypothermic preserved islets by its antioxidative and anti-inflammatory effect
Q Yao, X Jiang, ZW Huang, QH Lan, LF Wang… - …, 2019 - journals.lww.com
… Thus, proper preservation is crucial before collecting enough islets for transplantation. … To
evaluate the protective role of bilirubin in oxidative stress caused islet loss, we pretreated islets …
evaluate the protective role of bilirubin in oxidative stress caused islet loss, we pretreated islets …
Considerations for an alternative site of islet cell transplantation
P Addison, K Fatakhova… - Journal of Diabetes …, 2020 - journals.sagepub.com
… been the de facto site of islet transplantation. Technically, this site … insulin circulation, islets
transplanted into the liver are … to the islet cell-adrenal cell culture prior to transplant have been …
transplanted into the liver are … to the islet cell-adrenal cell culture prior to transplant have been …
[HTML][HTML] Culture on a native bone marrow-derived extracellular matrix restores the pancreatic islet basement membrane, preserves islet function, and attenuates islet …
H Wang, S Li, Q Dai, A Gonzalez, ON Tran… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
… In this study, we describe a new approach for preparing islets that enhances islet function …
, prior to islet transplantation. Compared to islets cultured on tissue culture plastic (TCP), islets …
, prior to islet transplantation. Compared to islets cultured on tissue culture plastic (TCP), islets …
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