[HTML][HTML] Kidney cells regeneration: dedifferentiation of tubular epithelium, resident stem cells and possible niches for renal progenitors

NV Andrianova, MI Buyan, LD Zorova… - International journal of …, 2019 - mdpi.com
Cells isolated from the S3 segment of adult rat kidneys were able to reconstruct a three-…
of renal progenitor cells [91]. However, it still remains unclear whether these cells belong to a …

[PDF][PDF] Generation of human renal vesicles in mouse organ niche using nephron progenitor cell replacement system

T Fujimoto, S Yamanaka, S Tajiri, T Takamura, Y Saito… - Cell Reports, 2020 - cell.com
… of the regeneration of human kidneys derived from human iPSC-derived … renal progenitor
cells (RPCs) were injected under the renal capsule. Injected metanephros (MNs) were isolated

[HTML][HTML] Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance

J Huang, Y Kong, C Xie, L Zhou - Stem Cell Research & Therapy, 2021 - Springer
kidney protection. In this review, we generally summarize the main stem/progenitor cells
derived from kidney … We also elaborate on the kidney-specific microenvironment that allows stem

Kidney‐in‐a‐lymph node: a novel organogenesis assay to model human renal development and test nephron progenitor cell fates

MG Francipane, B Han, L Oxburgh… - Journal of tissue …, 2019 - Wiley Online Library
… ectopic human kidney grafts … human fetal primary kidney tissues, we next asked whether it
could also support functional maturation of isolated or artificially created nephron progenitors (…

[PDF][PDF] A modular differentiation system maps multiple human kidney lineages from pluripotent stem cells

H Tsujimoto, T Kasahara, S Sueta, T Araoka… - Cell reports, 2020 - cell.com
… Our selective differentiation protocols should contribute to understanding the mechanisms
underlying human kidney development and disease and also supply cell sources for …

[HTML][HTML] Adult renal stem/progenitor cells can modulate T regulatory cells and double negative T cells

C Curci, A Picerno, N Chaoul, A Stasi… - International Journal of …, 2020 - mdpi.com
Adult Renal Stem/Progenitor Cells (ARPCs) have been recently identified in the human
kidney … and VFDL performed isolation and characterization of ARPCs from human renal tissue; …

Generating kidney from stem cells

MH Little, LJ Hale, SE Howden… - Annual review of …, 2019 - annualreviews.org
… To this end, many studies have used either human kidney cell lines or isolated primary
kidney cells from cadaveric renal tissue cultured in vitro in 2D or 3D formats using complex …

[PDF][PDF] Ex vivo expanded 3D human kidney spheres engraft long term and repair chronic renal injury in mice

O Harari-Steinberg, D Omer, Y Gnatek, O Pleniceanu… - Cell Reports, 2020 - cell.com
renal cell therapy and kidney regeneration and repair using progenitor cell types physiologically
intrinsic to kidney … nSPH-derived cells isolated from healthy kidneys have regenerative …

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

SV Kumar, PX Er, KT Lawlor, A Motazedian… - …, 2019 - journals.biologists.com
Kidney organoids have … kidney cell types in vitro. We describe here a modified suspension
culture method for the generation of kidney micro-organoids from human pluripotent stem cells

[HTML][HTML] The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells

MS Rahman, W Wruck, LS Spitzhorn, L Nguyen… - Scientific reports, 2020 - nature.com
… and genes associated with temporal maturation during human kidney organoids formation
from human iPSCs 50,51 . We propose that using native renal stem cells isolated directly from …