… Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL):
analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) …

… A total of 14 (3%) patients had ALL with TCF3-PBX1 detected by karyotyping (n = 10) and/or
FISH analysis (n = 10). Karyotyping, FISH and SNP array analysis revealed the unbalanced …

… karyotyping from both adult and pediatric patients respectively [23,24,25]. However, two of
these reports have not evaluated the karyotyping data with other prognostic factors … ALL [25]. …

… Cytogenetic classifications were performed based on anticipated prognostic factors in this …
demonstrated the independent prognostic value of low hypodiploidy and complex karyotype in …

… Along with response to treatment, these abnormalities are important prognostic factors.
Disease-risk stratification and the development of intensified chemotherapy protocols …

… enrolled in four different GIMEMA protocols, all based on a … chromosome-positive acute
lymphoblastic leukemia carry an average … of additional karyotypic aberrations in Ph+ ALL. These …

… MDS (eg, deletions of chromosomes 5, 7, 11, 13, 17, and 20 and trisomy 8), whereas
MDS-like karyotype was noted in 7% (7/100) of dn-ALL patients and was not observed in the pm-…

… Nowadays, MRD is the strongest independent prognostic factor in ALL. It is detected by
molecular methods that use leukemia-specific or patient-specific molecular markers (fusion gene …

… 95 (BFM-95) protocol and adults on UKALL 14 protocol. In a … Normal karyotype was seen
in 219 of 1419 (15%) samples … could be analysed in all cases, normal karyotype was seen in …

SciELO - Brasil - Prognostic significance of a normal karyotype in adult patients with BCR-ABL1-positive
acute lymphoblastic leukemia in the tyrosine kinase inhibitor era Prognostic …