A New Kavalactone Dimer from Piper methysticum

JX Yang - Chemistry of Natural Compounds, 2019 - Springer
… of Piper methysticum (kava). Their structures were determined by spectroscopic methods, …
, dd, J = 8.0, 2.0 Hz), and together with the 13 C NMR spectra, revealed one 1,2,4-trisubstituted …

A New Kavalactone Dimer from Piper methysticum

JX Yang - Chemistry of Natural Compounds, 2023 - Springer
Their structures were determined by spectroscopic methods, … The 13 C NMR and DEPT
spectra (Table 1) indicated thirty one … Finally, the overall structure of 1 was proved by analysis of …

A UHPLC-UV Method Development and Validation for Determining Kavalactones and Flavokavains in Piper methysticum (Kava)

Y Tang, C Fields - Molecules, 2019 - mdpi.com
… and kava CO 2 extract samples were applied for the analysis … retention times and UV spectra
to the reference standards. … there is a large difference in the total content of kava lactones

The protective effects of Kava (Piper Methysticum) constituents in cancers: a systematic review

A Celentano, A Tran, C Testa… - Journal of Oral …, 2019 - Wiley Online Library
There is growing interest about their potential impact on … literature surrounding Kava and
its potential anticancer … A single publication analysed the effect of the Kava constituent FKB in …

Isolation and Identification of Constituents Exhibiting Antioxidant, Antibacterial, and Antihyperuricemia Activities in Piper methysticum Root

TN Minh, TM Van, TD Khanh, TD Xuan - Foods, 2022 - mdpi.com
… The aqueous extract of kava (Piper methysticum) root is … , 1 H and 13 C NMR and X-ray
analyses. The structure elucidation of … The 1 H and 13 C NMR spectrum of C3 displayed a typical …

[HTML][HTML] Chemical and in vitro toxicity analysis of a supercritical fluid extract of Kava kava (Piper methysticum)

GE Petersen, Y Tang, C Fields - Journal of ethnopharmacology, 2019 - Elsevier
… extract of kava on cell proliferation and viability with that of its root source, a noble variety
of … of retention time and UV spectra to that of kavalactone and flavokavain standards. …

[HTML][HTML] Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus …

HMPD Herath, S Preston, A Jabbar… - International Journal for …, 2019 - Elsevier
analysed by 1 H nuclear magnetic resonance (NMR) … and the 1 H and 13 C NMR chemical
shifts were referenced to … GNT at 48 h and of a representative kavalactone (DMY) at 42 h, we …

In vitro inhibition of carboxylesterase 1 by Kava (Piper methysticum) Kavalactones

PW Melchert, Y Qian, Q Zhang, BO Klee, C Xing… - Chemico-biological …, 2022 - Elsevier
… of kava and its kavalactones on carboxylesterase 1 (CES1) in an in vitro system and established
associated kinetic parameters. Kava and its kavalactones … mass spectrometric analysis

Kavalactones from Kava (Piper methysticum) root extract as modulators of recombinant human glycine receptors

NH Hegazy, HG Breitinger, U Breitinger - Biological chemistry, 2019 - degruyter.com
… weight of kavalactones, and some of its isolated constituents … from IC50 analysis is drawn
(dotted line), indicating that kava … chromatography-mass spectrometry (GC-MS) analysis. The …

12 A Comprehensive Review

V Parcha, P Bhandari, S Chhetri… - Medicinal Roots and …, 2023 - books.google.com
spectra and separation techniques on the rhizomes of kava … review and analysis of the
evidence for kava having anxiolytic … bioactive components in Kava (Piper methysticum). Evidence-…