Kidney perfusion as an organ quality assessment tool—are we counting our chickens before they have hatched?

J De Beule, I Jochmans - Journal of Clinical Medicine, 2020 - mdpi.com
perfusion with static cold storage of DCD kidneyskidney perfusion by the Cochrane
systematic review [33,48]. The same group showed that kidney assessment during warm perfusion

Physiological effects of altering oxygenation during kidney normothermic machine perfusion

TD Adams, SA Hosgood… - … of Physiology-Renal …, 2019 - journals.physiology.org
kidney retrieval and perfusion, we designed two experiments to interrogate the effects of
reducing Pp O 2 on kidney … In kidneys exposed to either short or long cold ischemic times, we …

Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial

I Jochmans, A Brat, L Davies, HS Hofker… - The Lancet, 2020 - thelancet.com
… transplantation improves survival and quality of life, making it the preferred treatment for
end-stage renal disease, but many grafts fail prematurely. The introduction of effective …

Prolonged ex-vivo normothermic kidney perfusion: the impact of perfusate composition

MBF Pool, TL Hamelink, H van Goor… - PLoS …, 2021 - journals.plos.org
… This HMP machine preserved kidneys with cold (0–4C) UW machine perfusion solution (Belzer
UW-MP solution, Bridge to Life Ltd, Columbia, SC) for 2–4 hours using oxygenated …

Cold preflush of porcine kidney grafts prior to normothermic machine perfusion aggravates ischemia reperfusion injury

G Fabry, BM Doorschodt, T Grzanna, P Boor, A Elliott… - Scientific reports, 2019 - nature.com
… effect of cold preflush without subsequent cold storage. … cold preflush before normothermic
perfusion (PFNMP) aggravates kidney graft injury in comparison to normothermic perfusion

[HTML][HTML] Perfusate Composition and Duration of Ex-Vivo Normothermic Perfusion in Kidney Transplantation: A Systematic Review

A Fard, R Pearson, R Lathan… - Transplant …, 2022 - frontierspartnerships.org
Ex-vivo normothermic perfusion (EVNP) is an emerging strategy in kidney preservation that
enables resuscitation and viability assessment under pseudo-physiological conditions prior …

Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation

SJ Tingle, RS Figueiredo, JAG Moir… - Cochrane Database …, 2019 - cochranelibrary.com
perfusion. Two studies reported hypothermic machine perfusion prolongs the length of time
that donated kidneys … The effect of HMP on other outcomes (incidence of acute rejection, …

Oxygen consumption by warm ischemia-injured porcine kidneys in hypothermic static and machine preservation

J Kaminski, PO Delpech, S Kaaki-Hosni… - Journal of Surgical …, 2019 - Elsevier
renal transplantation. Hypothermic preservation is implemented either as static cold storage
(SCS) or as hypothermic machine perfusion … In the LifePort machine, the renal perfusion rate …

[图书][B] Exercise in the Heat: Implications on Kidney Function and Acute Kidney Injury

CL Chapman - 2020 - search.proquest.com
… Zac would want the y-axis values in the physiologic range, and Iheat may harm the kidney,
which is likely multifactorial and … in renal perfusion, depletion of ATP in renal epithelial cells, …

Brief normothermic machine perfusion rejuvenates discarded human kidneys

AM Hameed, DB Lu, E Patrick, BO Xu, M Hu… - Transplantation …, 2019 - journals.lww.com
… fashion, after aortic cannulation and cold perfusion with Soltran (kidney-only donor) and/or …
cava immediately upon commencement of cold perfusion. Kidneys were stored in the final …