Maintaining distance within the genome: the role of Sen1 and RNases H

U Aiello - 2021 - theses.fr
… In the first part, I will discuss the most important facets of transcription, focusing on RNA
polymerase II function. The second chapter will address how cells cope with the challenging task …

Sen1 is required for RNA Polymerase III transcription termination in an R-loop independent manner

J Rivosecchi, M Larochelle, C Teste, F Grenier… - bioRxiv, 2019 - biorxiv.org
transcription termination at a subset of RNA polymerase II … also contributes to transcription
termination at other classes … efficient Senataxin Sen1 -dependent transcription termination

[HTML][HTML] RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination

JF Victorino, MJ Fox, WR Smith-Kinnaman… - PLoS …, 2020 - journals.plos.org
… proteins are produced by the enzyme RNA Polymerase II. In this work, we … RNA Polymerase
II progression from the start of transcription to the 3’ end of the gene where the nascent RNA

[PDF][PDF] Sen1 is a master regulator of transcription-driven conflicts

U Aiello, D Challal, G Wentzinger, A Lengronne… - bioRxiv, 2022 - researchgate.net
RNA polymerase II at TRCs within genes and the rDNA, but also at sites of transcription-transcription
, thus providing a signature of Sen1-dependent conflicts. Assuming that conflicts …

Modulated termination of non-coding transcription partakes in the regulation of gene expression

N Haidara, M Giannini, O Porrua - Nucleic Acids Research, 2022 - academic.oup.com
… nascent RNA and induce the release of RNA polymerase II (… , the efficiency of Sen1-dependent
transcription termination. … Indeed, we have analysed the kinetics of ZAP1 repression by …

[PDF][PDF] Knowing when to stop: transcription termination on protein-coding genes by eukaryotic RNAPII

JB Rodríguez-Molina, S West, LA Passmore - Molecular cell, 2023 - cell.com
… Here, we review eukaryotic transcription termination by RNA polymerase II (RNAPII), …
is a link between transcription termination and chromatin marks of active transcription.Readthrough …

Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation

C Yague-Sanz, Y Vanrobaeys… - Genes & …, 2020 - genesdev.cshlp.org
Transcription by RNA polymerase II (RNAPII) is a dynamic … in RNAPII elongation kinetics
has remained unclear. Here we … would increase the competition between proximal and distal …

[PDF][PDF] DNA-directed termination of RNA polymerase II transcription

Z Han, GA Moore, R Mitter, DL Martinez, L Wan… - Molecular cell, 2023 - cell.com
… , by preventing interference between transcription units.Likewise, … of RNA polymerase II
(RNAPII) transcription initiation is well established,4–6 the precise mechanism of termination

[PDF][PDF] Widespread backtracking by RNA Pol II is a major effector of gene activation, 5′ pause release, termination, and transcription elongation rate

RM Sheridan, N Fong, A D'Alessandro, DL Bentley - Molecular cell, 2019 - cell.com
… of the RNA cleavage activity that rescues backtracked pol II, … WT TFIIS will compete with
TFIISDN for binding to pol II in … dictated by a kinetic competition between two enzymes moving …

RNA Polymerase II CTD phosphatase Rtr1 prevents premature transcription termination

MJ Fox, JF Victorino, WR Smith-Kinnaman, SAP Justice… - bioRxiv, 2019 - biorxiv.org
… proteins are produced by the enzyme RNA Polymerase II. In this work, we … RNA Polymerase
II progression from the start of transcription to the 3’ end of the gene where the nascent RNA