[PDF][PDF] Sen1 is recruited to replication forks via Ctf4 and Mrc1 and promotes genome stability

R Appanah, EC Lones, U Aiello, D Libri, G De Piccoli - Cell reports, 2020 - cell.com
DNA replication and RNA transcription compete for the same … with nascent RNA exiting
from a stalled RNA polymerase II (… arise during DNA replication, we analyzed the kinetics of …

The nucleosome DNA entry-exit site is important for transcription termination in Saccharomyces cerevisiae

AE Hildreth, MA Ellison, AM Francette, JM Seraly… - bioRxiv, 2020 - biorxiv.org
… facilitate termination by serving as a barrier to RNA polymerase II progression and highlight
the importance of the DNA … Through kinetic competition with elongating Pol II (23), Sen1, a …

A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation

KY Lee, A Chopra, GL Burke, Z Chen… - Nucleic Acids …, 2020 - academic.oup.com
… -K363R is associated with transcription termination defects in vivo and reduced RNA binding
affinity in vitro… Unravelling the means to an end: RNA polymerase II transcription termination

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription

AE Hildreth, MA Ellison, AM Francette, JM Seraly… - elife, 2020 - elifesciences.org
… activity on RNA polymerase II termination suggest widespread kinetic competition. …
determinants of Nrd1-Nab3-Sen1-dependent transcription termination. The EMBO Journal 31:3935–…

[PDF][PDF] Structure of mammalian RNA polymerase II elongation complex bound by α-amanitin and study of mammalian transcription termination and 3'end processing

X Liu - 2019 - ediss.uni-goettingen.de
RNA polymerase II (Pol II) is the central enzyme that transcribes eukaryotic protein-coding …
-amanitin binds Pol II and inhibits transcription at the step of RNA chain elongation. Pol II from …

Regulation of RNA polymerase II transcription by Spt4 in Saccharomyces cerevisiae

Ü Uzun - 2020 - ora.ox.ac.uk
termination, transcription of small non-coding RNAs including snRNAs and snoRNAs, are
terminated by the Nrd1, Nab3 and Sen1 dependent … a kinetic race between transcribing

Real-time single-cell characterization of the eukaryotic transcription cycle reveals correlations between RNA initiation, elongation, and cleavage

J Liu, D Hansen, E Eck, YJ Kim, M Turner… - PLOS Computational …, 2021 - journals.plos.org
… into, for example, intrinsic transcriptional noise in yeast [23], kinetic splicing effects in
human … A slow RNA polymerase II affects alternative splicing in vivo. Molecular Cell. 2003;12(2):525…

[图书][B] Regulation of RNA Synthesis and Decay via the C-terminal Domain of Pol II

SC Tseng - 2019 - search.proquest.com
RNA Polymerase II (Pol II) are canonically associated with being on the additive scale of the
balancing act between RNA … from the kinetic competition between transcribing Pol II and 5′ …

Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models

E Song, S Han, S Hohng, C Kang - Biochemical Society …, 2024 - portlandpress.com
… can occur at the first terminator, but if it fails, Sen1-dependent … cessation of transcription by
RNA polymerase II in the mouse … depends on kinetic coupling between RNA polymerase and …

Negative supercoil at gene boundaries modulates gene topology

YJ Achar, M Adhil, R Choudhary, N Gilbert, M Foiani - Nature, 2020 - nature.com
… context of Pol II-transcribed genes does not depend on Pol II and the … RNA polymerase
progression might depend strongly on Top1 in resolving topological stress in front of Pol II