Investigating the links between transcription and mRNA 3'end processing

SPA Chan - 2020 - ora.ox.ac.uk
RNA Polymerase II (Pol II) is responsible for transcribing all … extensive processing during
Pol II transcription in order to … kinetic coupling of transcription elongation, as pausing of Pol

The Mechanism of Transcription Termination by the PJW/PP1 Complex in Trypanosomatids

Y Zhang - 2023 - search.proquest.com
transcribed polycistronically by RNA polymerase II (RNAPII). Little is known about transcription
termination … RNAPII kinetics There is a kinetic competition between RNAP II and the 5’ to 3…

[PDF][PDF] Degradation of non-coding RNAs promotes recycling of termination factors at sites of transcription

T Villa, M Barucco, MJ Martin-Niclos, A Jacquier… - Cell Reports, 2020 - cell.com
… The occurrence of pervasive transcription originating from the promiscuity of RNA
polymerase II (RNAPII) initiation and intrinsic bidirectionality of promoters requires strict spatial …

Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast

S Topal, P Vasseur, M Radman-Livaja… - Nature …, 2019 - nature.com
transcription throughout the yeast cell cycle, and find that it regulates the distribution of RNA
Pol II … nucleosome assembly, as well as slower kinetics for restoration of a normal assembly …

Organismal benefits of transcription speed control at gene boundaries

X Leng, M Ivanov, P Kindgren, I Malik, A Thieffry… - EMBO …, 2020 - embopress.org
RNA polymerase II (RNAPII) transcription is crucial for gene expression. RNAPII density …
alters kinetic competition between transcriptional stalling, termination, and further elongation. …

Nrd1p identifies aberrant and natural exosomal target messages during the nuclear mRNA surveillance in Saccharomyces cerevisiae

P Singh, A Chaudhuri, M Banerjea… - Nucleic Acids …, 2021 - academic.oup.com
transcription termination pathway operates, influencing the stability of a few protein-coding
transcripts … Decay kinetics of representative transcription-elongation-defective ACT1-Tad and …

[图书][B] Spt5 and the Pol II Stalk Collaborate to Regulate Co-transcriptional pre-mRNA processing

ZA Morton - 2022 - search.proquest.com
RNA Polymerase II is responsible for transcribing the entirety … between Spt5’s central KOW
domains and the Pol II subunits … the contexts of transcription elongation and termination, Spt5 …

A transcriptional roadblock protects yeast centromeres

S Hedouin, GA Logsdon, JG Underwood… - Nucleic Acids …, 2022 - academic.oup.com
… from early log phase cultures or from G1 arrest/release kinetics was extracted using TRIzol
(… T7 RNA polymerase was added to initiate transcription and the resulting RNA products were …

So close, no matter how far: multiple paths connecting transcription to mRNA translation in eukaryotes

B Slobodin, R Dikstein - EMBO reports, 2020 - embopress.org
RNA polymerase II … Interestingly, while AUG-starting uORFs tend to compete with the main
ORF, mRNAs … complex effect on translation: reducing the kinetics of codon–anti-codon pairing …

Newly synthesized RNA sequencing characterizes transcription dynamics in three pluripotent states

R Shao, B Kumar, K Lidschreiber, M Lidschreiber… - bioRxiv, 2021 - biorxiv.org
… from TT-seq nascent RNA and RNA polymerase II occupancy and observe a transcriptome-…
Previous estimates of transcription elongation kinetics rely on chemical inhibition and time-…