Alteration of lateral habenula function prevents the proper exploration of a novel environment

L Lecourtier, L Durieux, V Mathis - Neuroscience, 2023 - Elsevier
… Hence, we can hypothesize that LHb dysfunction induced high levels of anxiety that affected
rat’s motivation during the most stressful session of the experiment (ie OF1) when animals …

Lateral Habenula Regulates Cardiovascular Autonomic Responses via the Serotonergic System in Rats

TH Doan, Y Sato, M Matsumoto… - Frontiers in …, 2021 - frontiersin.org
… The sympathetic nervous system accelerates the cardiovascular system and leads to …
and inhibiting noradrenaline reuptake elevate the noradrenaline level, and noradrenaline-induced …

… of glycine receptors in the lateral habenula rescues anxiety-and depression-like behaviors associated with alcohol withdrawal and reduces alcohol intake in rats

W Li, W Zuo, W Wu, QK Zuo, R Fu, L Wu, H Zhang… - …, 2019 - Elsevier
… in the LHb contribute to alcohol-related behaviors is unknown. Here, we report that rats
experiencing withdrawal from chronic alcohol consumption showed higher anxiety and sensitivity …

Lateral habenula and its potential roles in pain and related behaviors

D Dai, W Li, A Chen, XF Gao… - ACS chemical …, 2022 - ACS Publications
… (Kir4.1) are considered to contribute to induce burst firing and … depressive symptoms in cLH
rats, which suggests they may … causes arousal and anxiety, the release of norepinephrine in …

[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation

JL Ables, K Park, I Ibañez–Tallon - Pharmacological research, 2023 - Elsevier
… is the main site of norepinephrine production in the brain. For … cell types that may contribute
to nicotine’s action in the CNS. … behaviors regulated by the habenula in mice and rats. (AC) …

Multi-level variations of lateral habenula in depression: A comprehensive review of current evidence

GM Zhang, HY Wu, WQ Cui, W Peng - Frontiers in psychiatry, 2022 - frontiersin.org
… the primary source of norepinephrine in the central nervous … the mesocorticolimbic region in
rats with neonatal habenula lesions (155)… This presented paper contributes to expanding our …

[PDF][PDF] LATERAL HABENULA AND ENDOCANNABINOID REGULATION OF STRESS-RELATED BEHAVIOR

HR Wright - 2024 - rex.libraries.wsu.edu
rodents exposed to chronic stress exhibit impaired flexible decision-making and coping
behaviors. The lateral habenula (LHb) is a key brain region that contributes to … , and anxiety-like …

The cross-talk between dopaminergic and nitric oxide systems in the medial septal nucleus, and their distinct effects on anxiety-like behaviors in male rats

S Zarrabian, S Jamali, S Fazli-Tabaei… - Journal of Psychiatric …, 2021 - Elsevier
… in the modulation of anxiety-related behaviors in male rats. However, the cross-talk
between D1-like receptors differs from the one between D2-like receptors and the NO system. …

Anxiety during alcohol withdrawal involves 5-HT2C receptors and M-channels in the lateral habenula

R Fu, Q Mei, N Shiwalkar, W Zuo, H Zhang, D Gregor… - …, 2020 - Elsevier
… (Post-EtOH rats) exhibited robust anxiety-like behaviors (AB), … (M-channels) in the lateral
habenula (LHb); and that serotonin (… M-channels contribute to AB in adult male Long-Evans rats. …

A diverse network of pericoerulear neurons control arousal states

AT Luskin, L Li, X Fu, K Barcomb, T Blackburn… - BioRxiv, 2022 - biorxiv.org
… However, how local neuromodulatory inputs contribute to LC … (LC) is the primary source of
norepinephrine (NE) across the … , while inhibiting peri-LC GABA circuits increases anxiety-like …