… hepatic steatosis that progresses rapidly to NASH and liver … adiponectin or leptin improves
insulin sensitivity, which is … However, whether leptin administration can reverse NASH at …

… of lipodystrophy-associated NAFLD. These data suggest that leptin-mediated improvement
in insulin sensitivity … (metreleptin) in lipodystrophic patients improves hepatic steatosis and …

… leptin levels may support a diagnosis of lipodystrophy if low, … etiology of severe insulin
resistance disproportionate to BMI … therapies to reverse the underlying fat deficit in lipodystrophy. …

… lipid remodeling with reduced cardiac steatosis associated with adipose triglyceride lipase
(… that ATGL haploinsufficiency could reverse lipodystrophy, insulin resistance, and cardiac …

… diabetes, severe hypertriglyceridemia, and hepatic steatosis which may … leptin deficiency
and severe insulin resistance may affect reproductive function in patients with lipodystrophy…

… certain animal models may prevent hepatic steatosis, but, could, … Low leptin levels are a
hallmark of lipodystrophy; leptin … insulin resistance, diabetes that usually requires high insulin …

… lipodystrophy syndromes, such as insulin resistant diabetes, hypertriglyceridemia and hepatic
steatosis… of adipose tissue is able to reverse insulin resistance and associated metabolic …

… Data extraction focused on capturing abnormalities related to metabolic complications
associated with lipodystrophy (eg, insulin resistance, diabetes, dyslipidemia, hepatic steatosis) …

… showing that recombinant leptin improved insulin resistance and … in 8 patients presenting
GL and one patient with partial … Metreleptin was shown to reverse lipodystrophic features in two …

… of leptin, can be effective in certain forms of lipodystrophy … 1), infants show a generalised
lipoatrophy associated with an … (insulin resistance, hypertriglyceridemia, hepatic steatosis) …