… Our current influenza vaccine strategy is to make educated … representation of genetic repertoire
patterns typical in clonal lineages. (… (B) Convergence occurs in clonal lineages when two …

… Collectively, this high-resolution antibody repertoire analysis … and cataloguing clonally
expanded lineages, but PBs that may … -derived antibody responses to influenza vaccination in the …

… influenza vaccination triggers rapid recall of dozens of clonal B cell lineages in healthy
human … In summary, our results demonstrate that human antibody repertoires are shaped by a …

… cell lineages that characterized specific secondary responses in … that convergent antibody
sequence and structure may be a … responses to influenza vaccines. The existence of a ‘public …

… Further repertoire analysis in a subject vaccinated with the 2019–2020 seasonal influenza
vaccine identified similar sequences to our mAbs targeting the head domain from the 2017–…

… We present here an extensive structural and biophysical analysis of a lineage of BCRs …
of virus and B cell antigen receptor and for design of next-generation influenza vaccines. …

… influenza vaccines. In the current study, we report a lineage of naturally occurring human
antibodies … who was vaccinated with a trivalent seasonal split vaccine. The representative …

… influenza vaccines comprise two major formulations, inactivated vaccines and live attenuated
influenza vaccines (LAIVs… LAIVs are reported to induce mucosal IgA responses in children [ …

… States for seasonal influenza vaccination every year. Here we compare the impact of repeat
influenza vaccination on hemagglutination inhibition (HI) titers, antibody binding and affinity …

… flu vaccination elicits particularly strong serum antibody and … Lineage analysis (18) suggests
that both antibodies from D1 … of the influenza A virus antibody repertoire at day 28. These …