[PDF][PDF] Manipulation of lipid metabolism during normothermic machine perfusion: effect of defatting therapies on donor liver functional recovery
YL Boteon, J Attard, APCS Boteon… - Liver …, 2019 - Wiley Online Library
… pharmacological enhancement of the lipid metabolism of human livers during ex situ … Lipid
metabolism and functional assessment of discarded human livers with steatosis undergoing …
metabolism and functional assessment of discarded human livers with steatosis undergoing …
Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis
L Aoudjehane, J Gautheron, W Le Goff… - Disease models & …, 2020 - journals.biologists.com
… Indeed, we found that CHOP and GADD34 underwent a significant downregulation in their
… Although steatotic livers already make up a major proportion of discarded livers, we predict …
… Although steatotic livers already make up a major proportion of discarded livers, we predict …
Use of machine perfusion in livers showing steatosis prior to transplantation: a systematic review
… human livers discarded and not transplanted after perfusion; c) lacked sufficient details
on the biopsy-proven steatosis … % of organs with more advanced MaS underwent an HMP/HOPE …
on the biopsy-proven steatosis … % of organs with more advanced MaS underwent an HMP/HOPE …
Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies
S Raigani, N Karimian, V Huang, AM Zhang, I Beijert… - PloS one, 2020 - journals.plos.org
… , efficient energy utilization, and lipid metabolism. Steatotic … for oxidation while still being
insufficient for the degree of steatosis [… donors whose discarded liver was included in this study. …
insufficient for the degree of steatosis [… donors whose discarded liver was included in this study. …
[PDF][PDF] Banff consensus recommendations for steatosis assessment in donor livers
… uniformity in the assessment of donor steatosis. Donor livers discarded as being unsuitable
… deemed suitable for transplantation who subsequently underwent transplantation did well …
… deemed suitable for transplantation who subsequently underwent transplantation did well …
[HTML][HTML] NRF2 assessment in discarded liver allografts: A role in allograft function and salvage
… , we used a rat fatty-liver model, treating livers with an NRF2 … livers underwent further injury
and remained unsuitable for clinical use (unfilled red arrow). Lower panel: Hepatic steatosis …
and remained unsuitable for clinical use (unfilled red arrow). Lower panel: Hepatic steatosis …
Steatosis in liver transplantation: current limitations and future strategies
… [FGF]-19 and -21, lipid metabolism, intestinal transporters, intestinal microbiota, and endocrine
… , functional, and hemodynamic characterization of discarded human fatty livers during …
… , functional, and hemodynamic characterization of discarded human fatty livers during …
Mesenchymal stem cells ameliorate lipid metabolism through reducing mitochondrial damage of hepatocytes in the treatment of post-hepatectomy liver failure
J Wang, H Ding, C Pan, X Shi, H Ren - Cell Death & Disease, 2021 - nature.com
… After 24 h of incubation, unattached cells were discarded, … in the remaining liver of rats
undergoing hepatectomy and … by MSCs can affect liver steatosis induced by hepatectomy. IL-10 …
undergoing hepatectomy and … by MSCs can affect liver steatosis induced by hepatectomy. IL-10 …
Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice
JM Weiss, EM Palmieri, M Gonzalez-Cotto… - … Metabolism, 2023 - nature.com
… liver macrophages in a mouse model of NAFLD and human … Alb Cre mice that have the gene
deleted in hepatocytes (Fig. 2b)… recruited macrophages undergo reprogramming in the liver …
deleted in hepatocytes (Fig. 2b)… recruited macrophages undergo reprogramming in the liver …
Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion
D Patrono, R De Carlis, A Gambella… - Liver …, 2023 - journals.lww.com
… liver grafts having initially been discarded for liver transplantation (LT). However, its results in
the setting of significant (≥30%) macrovesicular steatosis (… cannulation, livers underwent a …
the setting of significant (≥30%) macrovesicular steatosis (… cannulation, livers underwent a …