… outcome measures that incorporate clinical and MRI data are best for predicting long-term …
Some evidence suggests that immunoglobulin M (IgM) OCBs could also be prognostic …

… NA Lipid-specific IgM-OCB are associated with worse long-term clinical progression CSF-…
complementary to 2-year brain parenchymal fraction change in predicting long-term outcomes. …

… the face of long-term outcomes. Moreover, … long-term outcomes evaluated in other studies
such as time to reach certain EDSS [8,9] and time to SP-MS [9], or different intended outcomes …

… The absence of lipid-specific IgM oligoclonal bands was the best … We studied in a multicenter
cohort of multiple sclerosis … efficacy of this drug in the long term was demonstrated (24). …

… important role in defining MS at the earliest stages, leading to better long-term clinical outcomes.
… CHI3L1 to predict conversion from CIS to MS [61,62,63,64]. It does not seem to predict …

… The CSF study included the determination of oligoclonal IgG … ), and lipid-specific oligoclonal
M bands (LS-OCMB) in CSF. … with poor prognosis in both the short term and long term (7). …

… risk factors may lead to better long-term outcomes and improve patients’ quality of life. MS
… , molecules which may be targeted by lipid-specific T cells and further orchestrate a Th1 pro-…

… event experienced a second relapse when lipid-specific IgM OCB were detected, compared
… Predicting aggressive multiple sclerosis with intrathecal IgM synthesis among patients with …

… represent a hallmark of multiple sclerosis (MS), … lipid-specific IgM OCBs, their presence
at onset is associated with a more aggressive disease course and worse long-term prognosis […

… long-term risks of adverse side effects have not yet been fully elucidated. Examination of
cerebrospinal fluid (CSF… diagnosis of MS subtypes, and predict the course of the disease, thus …