Lipoprotein (a)—the crossroads of atherosclerosis, atherothrombosis and inflammation
S Ugovšek, M Šebeštjen - Biomolecules, 2021 - mdpi.com
… a dynamic process similar to atherosclerosis. Endothelial cell dysfunction followed by
subendothelial accumulation of lipoproteins and chronic inflammation results in a condition that …
subendothelial accumulation of lipoproteins and chronic inflammation results in a condition that …
Apolipoprotein AI (ApoA-I), immunity, inflammation and cancer
K Georgila, D Vyrla, E Drakos - Cancers, 2019 - mdpi.com
… Apolipoprotein AI (ApoA-I), the major protein component of high density lipoprotein (HDL), …
In addition, by using a murine model of atherosclerosis, it was shown that myeloid Abca1/g1 …
In addition, by using a murine model of atherosclerosis, it was shown that myeloid Abca1/g1 …
[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis
MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
… of the apoB containing lipoproteins in one number … function (eg cholesterol efflux capacity).
Furthermore, we describe many beneficial properties of HDL that antagonize atherosclerosis …
Furthermore, we describe many beneficial properties of HDL that antagonize atherosclerosis …
Lipoprotein (a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options
A Rehberger Likozar, M Zavrtanik… - Annals of medicine, 2020 - Taylor & Francis
… Lp(a) has many functions, which include proatherosclerotic, prothrombotic and pro-inflammatory
roles. Here, we review recent data on the role of Lp(a) in the atherosclerotic process, …
roles. Here, we review recent data on the role of Lp(a) in the atherosclerotic process, …
[HTML][HTML] Critical roles of inflammation in atherosclerosis
J Moriya - Journal of cardiology, 2019 - Elsevier
… lipoprotein cholesterol. Thus, current understanding of the inflammatory mechanisms of
atherosclerosis … incident lung cancer and lung cancer mortality, although lung cancer was not a …
atherosclerosis … incident lung cancer and lung cancer mortality, although lung cancer was not a …
Inflammation in atherosclerosis—no longer a theory
P Libby - Clinical chemistry, 2021 - academic.oup.com
… the inflammation hypothesis of atherosclerosis in humans required a trial with an intervention
that reduced inflammation but did not alter atherogenic lipoproteins. … A decrease in cancer …
that reduced inflammation but did not alter atherogenic lipoproteins. … A decrease in cancer …
Lipoprotein (a) and its significance in cardiovascular disease: a review
FD Lau, RP Giugliano - Jama Cardiology, 2022 - jamanetwork.com
… The oxidized LDL portion is avidly taken up by macrophages to generate foam cells and
promote atherosclerotic plaque formation. Lp(a) is the only apoB-containing lipoprotein that …
promote atherosclerotic plaque formation. Lp(a) is the only apoB-containing lipoprotein that …
[HTML][HTML] Lipoprotein (a): an underestimated inflammatory mastermind
KE Dzobo, JM Kraaijenhof, ESG Stroes… - Atherosclerosis, 2022 - Elsevier
… Crohn's disease, diabetes multiple sclerosis, breast cancer and Alzheimer's disease [34].
Advanced human atherosclerotic plaques demonstrated that the autophagy protein ATG16L1 …
Advanced human atherosclerotic plaques demonstrated that the autophagy protein ATG16L1 …
What do we know about the role of lipoprotein (a) in atherogenesis 57 years after its discovery?
B Cybulska, L Kłosiewicz-Latoszek, PE Penson… - Progress in …, 2020 - Elsevier
… Elevated circulating concentrations of lipoprotein(a) [Lp(a)] is strongly associated with
increased risk of atherosclerotic cardiovascular disease (CVD) and degenerative aortic stenosis. …
increased risk of atherosclerotic cardiovascular disease (CVD) and degenerative aortic stenosis. …
Lipoproteins and cancer: The role of HDL-C, LDL-C, and cholesterol-lowering drugs
KK Patel, K Kashfi - Biochemical pharmacology, 2022 - Elsevier
… Its accumulation in the vasculature causes plaque formation and atherosclerosis, kidney
disease, and cancer. Several studies show that many oncogenic signaling pathways modulate …
disease, and cancer. Several studies show that many oncogenic signaling pathways modulate …