… intracellular pathogen that has been used for over 5 decades as a model to study basic …
depends on the expansion of antigen-specific CD8+ T-cells and establishment of memory …

… The current study was designed to investigate the role of … of pathogen clearance and the
magnitude of antigen-specific … in antigen-specific effector and memory CD8 + T cell response …

… intracellular bacterial model pathogen. … monocytogenes antigen. This prompted us to
employ a rapid prime-boost amplification strategy for studies of antigen-specific CD8 + T cells …

… Listeria monocytogenes serves as a model pathogen to … studies of CD8 T cell responses
following antigen-specific … (acute response), day 28 (after contraction), and day 70 (memory) are …

… a pathogenic infection. Cytosolic PRRs that sense L. … If memory CD8 + T cells are present,
they also localize to the red … peak number of antigen-specific CD8 T cells in peripheral blood …

… physiologic models of foodborne infection. Consequently, this … pathogen burden did not
rescue antigen-specific CD8 T cell … CD8 T cell responses (16, 17), mice used in this study also …

… of memory CD8 + T cells is crucial for host protection upon reencounter of the same pathogen.
… We will describe a bacterial infection model with Listeria monocytogenes, generally giving …

… infection with attenuated Listeria monocytogenes engineered to … pathogen to generate
Ag-specific memory CD4 T cells, our “… compared to what has been done for memory CD8 T cells, …

… We found that acute Listeria monocytogenes (L. … monocytogenes infection and monitor its
effect on pathogen-… that expansion of antigen-specific effector CD4 + T cells had occurred. …

… effective T cell-based immunity to a model intracellular pathogen, … attributes of antigen-specific
memory CD8 T cells induced by … intracellular pathogen Listeria monocytogenes. These …