Infectious Virus Persists in CD4+ T Cells and Macrophages in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques

CM Abreu, RT Veenhuis, CR Avalos, S Graham… - Journal of …, 2019 - Am Soc Microbiol
viral strains to accurately reproduce the neuropathic and immunologic events identified in
HIV… Spleen and lung cells were mechanically removed from tissues using an 18-gauge needle …

… of an intramuscular DNA/modified vaccinia Ankara vaccine for simian immunodeficiency virus is associated with better control of infection in orally exposed infant …

AD Curtis, KA Walter, R Nabi, K Jensen… - AIDS research and …, 2019 - liebertpub.com
… After flow cytometric analysis, an initial phagocytic score was determined by multiplying the
… , plasma viremia had dropped to 10 5 copies/mL in two of six infants but remained >10 6 …

Long-term protective immunity induced by an adjuvant-containing live-attenuated AIDS virus

T Okamura, Y Shimizu, MN Asaka, T Kanuma… - npj Vaccines, 2021 - nature.com
… constructed a live attenuated simian human immunodeficiency virus (SHIV) to … live
attenuated immunodeficiency viruses nef-deleted simian immunodeficiency virus (SIV) and simian

… show protection against highly pathogenic simian immunodeficiency virus (SIV) after vaccination with SIV gene-expressing BCG prime and vaccinia virus/Sendai virus …

S Kato, H Shida, T Okamura, X Zhang, T Miura… - Journal of …, 2021 - Am Soc Microbiol
… dual vaccine for human immunodeficiency virus type 1 (HIV-1) and … BCG, the highly attenuated
vaccinia virus LC16m8Δ strain, … This indicates that BCG Tokyo is cleared faster and is less …

Characterization of the persisting HIV-1 reservoir in early treated children on long-term suppressive ARV regimens

MGK Katusiime - 2019 - scholar.sun.ac.za
… In Aim I, we used a sensitive quantitative PCR assay for HIV-1 cell associated DNA (iCAD),
followed by cellassociated DNA-single genome sequencing (CAD-SGS) of 1200bp in HIV-1 …

Long-term sterile immunity induced by an adjuvant-containing live-attenuated AIDS virus

T Okamura, Y Shimizu, T Kanuma, Y Tsujimura… - bioRxiv, 2020 - biorxiv.org
… a live attenuated simian human immunodeficiency virus to … The live attenuated
immunodeficiency viruses nef-deleted … safe to use as a template for HIV vaccines in humans …

Intravenous Bacille Calmette–Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis

EC Larson, AL Ellis-Connell, MA Rodgers… - Nature …, 2023 - nature.com
… consideration especially for live attenuated vaccines such as … , the timing of when BCG
is fully cleared. A self-limiting … on a haemocytometer were multiplied by the frequency of the …

Characterization of a Plasmid-Based DNA Vaccine for Simian Immunodeficiency Virus

P Sanipara - 2020 - egrove.olemiss.edu
… SIV (Simian Immunodeficiency Virus) as a model for HIV for … This treatment is effective in
controlling viral multiplication and … Partially deleted Nef protein is able to re-arrange itself back …

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

MB Shapiro, T Cheever, DC Malherbe… - Nature …, 2020 - nature.com
… for most human immunodeficiency virus (HIV) infection in … oral exposure cleared simian-human
immunodeficiency virus (… µl blood was calculated by multiplying the absolute lymphocyte …

Deletion of both the tyrosine-based endocytosis signal and the endoplasmic reticulum retrieval signal in the cytoplasmic tail of spike protein attenuates porcine …

Y Hou, T Meulia, X Gao, LJ Saif, Q Wang - Journal of virology, 2019 - Am Soc Microbiol
… may aid in the design of efficacious live attenuated vaccines … (SIV) and human
immunodeficiency virus (HIV) attenuated … this channel was determined by multiplying the cell area …