Effects of prenatal hypoxia on nervous system development and related diseases

B Wang, H Zeng, J Liu, M Sun - Frontiers in neuroscience, 2021 - frontiersin.org
… on brain development and behavioral phenotypes, and the … Rats and mice are the most
popular and convenient rodent … Brain damage caused by hypoxia has a long-term effect on the …

Reelin alterations, behavioral phenotypes, and brain anomalies in schizophrenia: a systematic review of insights from rodent models

AC Sánchez-Hidalgo, C Martín-Cuevas… - Frontiers in …, 2022 - frontiersin.org
… A similar study with 6-month-old mice evaluating the long-term effects of prenatal hypoxia
described significant changes specific to the HRM model, such as decreased frontal cortex …

Data_Sheet_1_Reelin Alterations, Behavioral Phenotypes, and Brain Anomalies in Schizophrenia: A Systematic Review of Insights From Rodent Models. pdf

AC Sánchez-Hidalgo, C Martín-Cuevas… - 2022 - digital.csic.es
… the long-term effects of glucocorticoid stimulation on memory in … rescues schizophrenia-like
phenotypes in a mouse model of … cortex in prenatal hypoxic miceand HRM, and HP in HRM. …

Application of animal experimental models in the research of schizophrenia

P Wang, M Li, A Zhao, J Ma - American Journal of Medical …, 2021 - Wiley Online Library
… , in which the schizophrenia-like phenotype of the male … will impair the long-term
potentiation/long-term inhibition (LTP/LTD) … changes in the heterozygous Reeler mice are very …

Corticosterone antagonist or TrkB agonist attenuates schizophrenia-like behavior in a mouse model combining Bdnf-e6 deficiency and developmental stress

Y Chen, S Li, T Zhang, F Yang, B Lu - Iscience, 2022 - cell.com
… (Bdnf-e6 −/− ), when exposed to postnatal stress including hypoxia or social isolation, …
Effects of prenatal hypoxia on schizophrenia-related phenotypes in heterozygous reeler mice

Deficits in seizure threshold and other behaviors in adult mice without gross neuroanatomic injury after late gestation transient prenatal hypoxia

AG Cristancho, EC Gadra, IM Samba, C Zhao… - Developmental …, 2022 - karger.com
… that late gestation transient prenatal hypoxia in mice is a simple, … of the long-term effects
of hypoxia on the developing brain. … phenotype from prenatal hypoxia in exposed offspring. …

Interaction of reelin and stress on immobility in the forced swim test but not dopamine-mediated locomotor hyperactivity or prepulse inhibition disruption: Relevance to …

MJ Notaras, B Vivian, C Wilson… - Schizophrenia Research, 2020 - Elsevier
Effect of chronic CORT treatment on PPI and startle in heterozygous reelin mouse (HRM)
and wildtype (WT) controls at baseline and following challenge with apomorphine (A, C, E) and …

Polymorphisms in the hypoxia inducible factor binding site of the macrophage migration inhibitory factor gene promoter in schizophrenia

S Okazaki, S Boku, Y Watanabe, I Otsuka, T Horai… - Plos one, 2022 - journals.plos.org
effect of hypoxia on MIF expression in primary cultured astrocytes derived from neonatal mice
… In human research, there is consistent evidence linking perinatal hypoxia to SCZ in later …

Early Postnatal Exposure to Intermittent Hypercapnic Hypoxia (IHH), but Not Nicotine, Decreases Reelin in the Young Piglet Hippocampus

V Despotovski, A Vivekanandarajah, KA Waters… - Neurotoxicity …, 2022 - Springer
This study evaluated the expression of reelin, an extracellular protein involved in lamination
and migration of neurons, in the hippocampus of young piglets, and quantified to examine …

In Vitro and In Vivo Models for the Investigation of Potential Drugs Against Schizophrenia.

AA Kaczor, E Kȩdzierska, O Koszła… - Biomolecules …, 2020 - search.ebscohost.com
… period disrupted long-term potentiation/long term depression (… studies infection, malnutrition,
or hypoxia in the fetus are the … receptor, reverses schizophrenia-like cognitive and social …