… reduce scarring and adverse left ventricular remodelling. The … in animal models of acute MI
as evidenced by smaller infarct … infarct size and affording long-term improvements in cardiac …

… β-adrenergic responsiveness and prevent left ventricular diastolic dysfunction in a large …
a non-reperfused MI that cannot be thoroughly reproduced in an experimental animal model. …

… animal models. Rather than list an exhaustive inventory of differences between reperfused
versus nonreperfused … useful for studies of infarct mechanics and long-term LV structural and …

… strategies to limit myocardial infarction depends on the duration … strategies designed to target
non-reperfused myocardium. … that are effective in animal models have failed to translate to …

… To address this question, we studied the effects of long-term … failure and remodeling
characteristic of nonreperfused … to confirm these findings in large animal models, in view of future …

… of myocardial diseases, including acute myocardial infarction … Most studies in animal models
using pharmacological or … 2 (TGFβR2)) subjected to non-reperfused MI demonstrated that …

… functionality after an ischemic insult, even in the long term, … in a mouse and rat model of
myocardial infarction 38 . The genetic … dysfunction in a mouse model of non-reperfused MI 40 . …

… have recently shown in a rat model of myocardial infarction (MI)-… induced iron deficiency
impaired long term prognosis, this single … non-reperfused MI). Last but not least, iron therapy was …

… to have increased cardiac injury and poorer long‐term ventricular function. … in cardiac
healing after MI in animal models. Most studies have been performed in mice with nonreperfused …

… infarct size or long-term scar size, post-infarct remodeling, cardiac dysfunction, or mortality in
non-reperfused … of the left ventricular free wall, which encompasses the infarct zone, with an …