Celastrol-type HSP90 modulators allow for potent cardioprotective effects

H Aceros, S Der Sarkissian, M Borie, LM Stevens… - Life sciences, 2019 - Elsevier
… In ex vivo I/R rat models, HO-1 expression is induced at the … long-term effects on cicatrisation,
development of ventricular … and non-reperfused myocardial infarction in vitro and ex vivo …

Endogenous mechanisms of vascular regeneration following myocardial infarction

EG Solomonidis - 2022 - era.ed.ac.uk
… In non-reperfused, fatal MI, the infarct area is visible in … at decreasing infarct size, incidence
of heart failure and long term-… As a result, we need robust and reproducible animal models

Determinants of Reperfusion Injury in the Diabetic Heart

IJ Harding - 2019 - discovery.ucl.ac.uk
… Here, I investigate if animal model of diabetes can be used to … MRI in a mixed population
of reperfused and non-reperfused … Adverse cardiac remodelling continues over the long term

NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful

AG Mauro, E Mezzaroma, S Toldo, GC Melendez… - Translational …, 2023 - Elsevier
… In contrast, long-term cancer survivors may remain … in reperfused and non-reperfused
myocardial infarction models. … Pre-clinical murine and rat models have shown that trastuzumab …

Diagnosis of myocardial infarction at autopsy: AECVP reappraisal in the light of the current clinical classification

K Michaud, C Basso, G d'Amati, C Giordano, I Kholová… - Virchows Archiv, 2020 - Springer
… A more recently described long-term complication is the … at anastomosis sites, low left
ventricular output failure or poor run-off … pronounced when compared with non-reperfused MI, …

Effect of ivabradine on cardiac arrhythmias: Antiarrhythmic or proarrhythmic?

M Marciszek, A Paterek, M Oknińska, Z Zambrowska… - Heart Rhythm, 2021 - Elsevier
… total mortality in the rat model of nonreperfused acute MI, … in acute ST-elevation myocardial
infarction, enrolling in total over … In the model of acute nonreperfused MI in the rat, we showed …

Molecular and cellular differences in cardiac repair of male and female mice

AB Pullen, V Kain, CN Serhan… - … of the American Heart …, 2020 - Am Heart Assoc
… measured longterm survival, cardiac function, myocardium … resolvins of the left ventricle
at myocardial infarction (MI)‐day … )–derived SPM moieties of the left ventricle at MI‐d1 of male …

[PDF][PDF] Part 2: Arrhythmias in Ischemic Heart Disease

HL Roderick, P Claus, R Willems… - … OF VENTRICULAR …, 2022 - lirias.kuleuven.be
… small-animal models for the study of BZ and remote regions, is the difficulty of regional …
are the logistics of handling adult pigs during long-term experiments. Logistically, sheep are …

The fate and role of the pericytes in myocardial diseases

NG Frangogiannis - European Journal of Clinical Investigation, 2024 - Wiley Online Library
… Electron microscopic analysis suggested that left ventricular mural … of cardiac rupture in the
mouse model of nonreperfused … circulation in a rat model of acute myocardial infarction. PLoS …

The interplay of galectins-1,-3, and-9 in the immune-inflammatory response underlying cardiovascular and metabolic disease

AA Mansour, F Krautter, Z Zhi, AJ Iqbal… - Cardiovascular …, 2022 - Springer
… Other studies looked at Gal-3 binding protein which was also increased in plasma levels
of coronary artery disease patients and was associated with long-term mortality [86]. …