Cerebrospinal fluid and MRI biomarkers in neurodegenerative diseases: A retrospective memory clinic-based study

A Kaipainen, O Jääskeläinen, Y Liu… - Journal of …, 2020 - content.iospress.com
patients with subjective or objective cognitive impairment who underwent neurological, CSF
biomarker … ) and T1-weighted MRI examinations at Kuopio University Hospital. We assessed …

Clinical and biomarker trajectories in sporadic Alzheimer's disease: A longitudinal study

HF Wang, XN Shen, JQ Li, J Suckling… - … & Dementia …, 2020 - Wiley Online Library
Longitudinal changes of biomarkers among different stages were … rates of change to calculate
the biomarker trajectories in … information), but CSF tau in patients with dementia due to AD …

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

A Lleó, D Alcolea, P Martínez-Lage, P Scheltens… - … & Dementia, 2019 - Elsevier
… Although we could not detect a longitudinal change in t-tau and p-tau levels in our study…
change in the trajectories of tau markers in the dementia phase of AD. The decreases in the CSF

Longitudinal brain atrophy and CSF biomarkers in early-onset Alzheimer's disease

J Contador, A Pérez-Millán, A Tort-Merino, M Balasa… - NeuroImage: Clinical, 2021 - Elsevier
… We used the symmetrized percent change (spc) to evaluate longitudinal changes in CTh,
calculated as the rate of thickness change (CTh at time2 – CTh at time1) divided by the …

Evolution of Alzheimer's disease cerebrospinal fluid biomarkers in early Parkinson's disease

DJ Irwin, J Fedler, CS Coffey… - Annals of …, 2020 - Wiley Online Library
… in the longitudinal change in biomarkers, we find modest but measurable group-wise changes
in AD CSF biomarkers … Importantly, we find that the longitudinal profile in patients with PD …

Tau protein is associated with longitudinal memory decline in cognitively healthy subjects with normal Alzheimer's disease cerebrospinal fluid biomarker levels

A Tort-Merino, J Olives, M León… - Journal of …, 2019 - content.iospress.com
… Regarding the longitudinal change in both the AFE-T and the … reserve) and biological (AD
CSF biomarkers) data and the … relationships between the longitudinal memory performance (…

Prediction of longitudinal cognitive decline in preclinical Alzheimer disease using plasma biomarkers

N Mattsson-Carlgren, G Salvadó, NJ Ashton… - JAMA …, 2023 - jamanetwork.com
Longitudinal change in both MMSE and mPACC scores in the BioFINDER-1 cohort … CSF
biomarkers, we also allowed CSF Aβ42/40 (which had a univariate association with longitudinal

Plasma and CSF neurofilament light: relation to longitudinal neuroimaging and cognitive measures

MM Mielke, JA Syrjanen, K Blennow, H Zetterberg… - Neurology, 2019 - AAN Enterprises
… in plasma NfL also tracked with short-term cognitive change. Blood-based biomarkers of
neurodegeneration have obvious advantages over both CSF and neuroimaging biomarkers. …

[HTML][HTML] Biomarker profiling beyond amyloid and tau: cerebrospinal fluid markers, hippocampal atrophy, and memory change in cognitively unimpaired older adults

AV Idland, R Sala-Llonch, LO Watne, A Brækhus… - Neurobiology of …, 2020 - Elsevier
… of CSF biomarkers with shared behavior across participants. In this analysis, all the available
CSF biomarkersLongitudinal change in memory function across biomarker groups. Upper …

Longitudinal changes in anger, anxiety, and fatigue are associated with cerebrospinal fluid biomarkers of Alzheimer's disease

GM Babulal, L Chen, JM Doherty… - Journal of …, 2022 - content.iospress.com
… Obtaining CSF biomarkers is specialized, costly, burdensome, and … longitudinal changes
in anger, tension/anxiety, and fatigue were associated with baseline preclinical AD biomarkers