Comparison of diazepam and lorazepam for the emergency treatment of adult status epilepticus: a systemic review and meta‐analysis

H Kobata, T Hifumi, E Hoshiyama… - Acute Medicine & …, 2020 - Wiley Online Library
… Our findings IN this systemic review suggested that lorazepam was superior to iv diazepam
in treating adult SE as first-line treatment, with no significant differences in undesirable effects…

[HTML][HTML] Medical management of status epilepticus: emergency room to intensive care unit

AA Crawshaw, HR Cock - Seizure, 2020 - Elsevier
… Either lorazepam or diazepam are suitable IV agents. Speed of administration and adequate
initial dosing are probably more important than choice of drug. Although only phenytoin (…

Pharmacologic management of status epilepticus

ED Wieruszewski, CS Brown, JG Leung… - AACN Advanced Critical …, 2020 - AACN
… routes have similar efficacy, intravenous lorazepam is preferred because of its … lorazepam
and diazepam formulations contain propylene glycol, which can accumulate and lead to acute

[HTML][HTML] Diagnosis and treatment of status epilepticus

SK Lee - Journal of Epilepsy Research, 2020 - ncbi.nlm.nih.gov
… IV lorazepam and diazepam showed equal efficacy,34 although lorazepam was favored …
versus intravenous lorazepam in the prehospital treatment of status epilepticus by paramedics. …

Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability

R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
… The conventional BZDs clonazepam, diazepam, lorazepam and … long been established in
the acute treatment of SE, other administration … for the treatment of prolonged seizures and SE. …

Optimal management of status epilepticus in children in the emergency setting: a review of recent advances

S Messahel, L Bracken, R Appleton - Open Access Emergency …, 2022 - Taylor & Francis
… of which the most common are buccal or intra-nasal midazolam, rectal diazepam and
intravenous lorazepam. Alternative drugs, for which there are considerably less RCT data, are intra-…

Time is brain: acute control of repetitive seizures and status epilepticus using alternative routes of administration of benzodiazepines

S Almohaish, M Sandler, GM Brophy - Journal of Clinical Medicine, 2021 - mdpi.com
… is absorbed more rapidly and predictably than IM lorazepam or diazepam and, therefore, is
… and IV lorazepam for status epilepticus, although time from drug administration to seizure

Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence

M Cruickshank, M Imamura, C Counsell, L Aucott… - Journal of …, 2022 - Springer
… Although definition of seizure cessation and of convulsive status epilepticus varied across …
(ie lorazepam, diazepam, and midazolam) were effective at stopping seizures in adults treated

Efficacy and Safety Comparison Between Lorazepam and Diazepam in Treating Convulsive Status Epilepticus in Children: An Evidence-Based Case Report

M Habiburrahman, WK Sarkowi - Asian Journal of Health Research, 2023 - a-jhr.com
… Some reports indicate diazepam being less … to-treat convulsive status epilepticus (CSE)
case in a 10-month infant who received diazepam, questioning if intravenous/rectal lorazepam is …

[HTML][HTML] Recognition and treatment of status epilepticus in the prehospital setting

S Maier, J Godau, J Bösel, J Rösche - Seizure, 2021 - Elsevier
… of treatment episodes of SE in patients with known epilepsy a BZD was given in an appropriate
way by bystanders. In nearly all treatment episodes with lorazepam (… received diazepam (…