Biological and Clinical Implications of Sex-Specific Differences in Alzheimer's Disease

JA Santiago, JA Potashkin - Sex and Gender Effects in Pharmacology, 2023 - Springer
… Several biomarkers have shown promise, but a definitive diagnostic test is yet to be found. …
Notably, all female subjects in this study were taking estrogen-dominant oral contraceptives; …

Neurological diseases: Sex and gender evidence in stroke, migraine, and Alzheimer's dementia

NT Aggarwal, RM Dafer - How Sex and Gender Impact Clinical Practice, 2021 - Elsevier
… that the sex and gender differences in many neurological … a lower risk of ischemic stroke
recurrence in subjects who … clinical presentation, diagnostic evaluation, treatment options, …

[HTML][HTML] Sex-specific association of endogenous PCSK9 with memory function in elderly subjects at high cardiovascular risk

PG Simeone, F Vadini, R Tripaldi, R Liani… - Frontiers in Aging …, 2021 - frontiersin.org
… T2DM diagnosis was made according to the ADA criteria (… We also found gender differences
in patterns of cognitive test … However, at least in our cohort, circulating leptin, although …

Biomarkers: our path towards a cure for Alzheimer disease

R Tarawneh - Biomarker insights, 2020 - journals.sagepub.com
… for fluid biomarkers in improving diagnostic accuracy, patient … -1), and lower levels of IL-1
receptor antagonist and leptin, in AD … markers of AD in the ADNI cohort suggest that vascular …

Proteomes of paired human cerebrospinal fluid and plasma: relation to blood–brain barrier permeability in older adults

L Dayon, O Cominetti, J Wojcik… - Journal of proteome …, 2019 - ACS Publications
… CDR, gender, and age; the position of the CSF and plasma … to predict BBB impairment with
a diagnostic accuracy of 91.38… , however, only 16 subjects had a BBB impairment, ie, a CSF/…

Biomarkers of insulin resistance, oxidative stress, and nutrition and the brain

KE McLimans - 2019 - search.proquest.com
… mild cognitive impairment (MCI), can improve diagnostic … 6% of subjects in the treatment
group developing meningoencephaltis (… ’s Disease Neuroimaging Initiative (ADNI) were used to …

The role of oxysterols in neurodegeneration: implications for cognitive function, maternal effects, and sex-specific differences

M Latorre Leal - 2024 - openarchive.ki.se
… , in subjects defined as AD cases, cognitive functions such as … Furthermore, leptin levels in
circulation seem to be lower in … Our results show that 24OH levels did not differ in diagnoses

Markers of Cerebrovascular Injury, Inflammation, and Plasma Lipids Are Associated with Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Cognitively Normal …

D Jansson, M Wang, RG Thomas… - Journal of …, 2022 - content.iospress.com
… all three features is necessary for a definitive diagnosis of AD [1], it … cognitively normal
subjects prior to any therapeutic intervention. While our cross-sectional study suggests that plasma

[PDF][PDF] Brain structural alterations detected by an automatic quantified tool as an indicator for MCI diagnosing in type 2 diabetes mellitus patients: A magnetic …

J Gu, S Cui, H Qi, J Li, W Wu, S Wang, J Ni, Z Miao - Heliyon, 2022 - cell.com
Background and objectives Type 2 diabetes mellitus (T2DM) is an important risk factors for
mild cognitive impairment (MCI). Structural magnetic resonance imaging (sMRI) is an …

Cognitive impairment in obesity and diabetes

C Carvalho, PI Moreira - Obesity and Diabetes: Scientific Advances and …, 2020 - Springer
… obesity and dementia is the gap in gender-inherent differences. It has been postulated that
… Obese subjects also present increased levels of circulating leptin, usually related to leptin