Epidermal growth factor receptor tyrosine kinase inhibitors for non‐small cell lung cancer harboring uncommon EGFR mutations: Real‐world data from Taiwan
JWC Chang, CY Huang, YF Fang, CF Chang… - … Cancer, 2023 - Wiley Online Library
… mutations and the poor response observed for exon 20 … gefitinib/erlotinib. Although most
EGFR-TKIs were not effective for exon 20 insertions, some patients benefited from treatment …
EGFR-TKIs were not effective for exon 20 insertions, some patients benefited from treatment …
Response to Standard Therapies and Comprehensive Genomic Analysis for Patients with Lung Adenocarcinoma with EGFR Exon 20 Insertions
NJ Choudhury, AJ Schoenfeld, J Flynn, CJ Falcon… - Clinical Cancer …, 2021 - AACR
… The suboptimal response to ICI observed among … poor activity in patients with NSCLC with
driver alterations. A series of EGFR-mutant lung cancers previously reported poor responses …
driver alterations. A series of EGFR-mutant lung cancers previously reported poor responses …
Successful treatment of lung adenocarcinoma with epidermal growth factor receptor compound mutations involving exon 19 deletion and exon 20 insertion by afatinib
T Ikeuchi, H Tokuyasu, S Ishikawa - Internal Medicine, 2019 - jstage.jst.go.jp
… A good response to afatinib was evident in our patient who had lung … Lung cancer with
epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment …
epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment …
… epidermal growth factor receptor tyrosine kinase inhibitors treatment and EGFR exon 19 deletion with frequency of the T790M mutation in non-small cell lung cancer …
W Gao, J He, SD Jin, J Xu, TF Yu, W Wang… - … and therapy, 2019 - Taylor & Francis
… who received gefitinib as a previous EGFR-TKI treatment had a … as well as the use of
low-sensitivity detection methods (false … a partial response to previous EGFR-TKI treatment had a …
low-sensitivity detection methods (false … a partial response to previous EGFR-TKI treatment had a …
[HTML][HTML] … responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with uncommon EGFR mutations: new insights and future …
A Russo, T Franchina, G Ricciardi, A Battaglia… - International Journal of …, 2019 - mdpi.com
… subgroup of Non-Small Cell Lung Cancers (NSCLCs), that … treated with gefitinib [41],
though they may better respond to … Human epidermal growth factor receptor 2 (HER2) exon 20-…
though they may better respond to … Human epidermal growth factor receptor 2 (HER2) exon 20-…
[HTML][HTML] Clinical characteristics of advanced non-small cell lung cancer patients with EGFR exon 20 insertions
C Morita, T Yoshida, M Shirasawa, K Masuda… - Scientific reports, 2021 - nature.com
… Epidermal growth factor receptor (EGFR) exon 20 insertion … with these EGFR mutations
respond to treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) such as gefitinib, erlotinib…
respond to treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) such as gefitinib, erlotinib…
[HTML][HTML] Co-occurring alterations of ERBB2 exon 20 insertion in Non-Small Cell Lung Cancer (NSCLC) and the potential indicator of response to afatinib
B Yuan, J Zhao, C Zhou, X Wang, B Zhu, M Zhuo… - Frontiers in …, 2020 - frontiersin.org
… epidermal growth factor receptor 2 (ERBB2, HER-2) exon 20 … it is probably caused by the
low detection rate of CNV due to … induced upon treatment with erlotinib or gefitinib (39, 40) and …
low detection rate of CNV due to … induced upon treatment with erlotinib or gefitinib (39, 40) and …
[HTML][HTML] Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: A review
EA Karlsen, S Kahler, J Tefay, SR Joseph, F Simpson - Cells, 2021 - mdpi.com
… mutations were related to the sensitivity of NSCLC to gefitinib, … that predicted poor outcomes
and poor response to therapy [… or afatinib for the treatment of exon 20 insertion tumours have …
and poor response to therapy [… or afatinib for the treatment of exon 20 insertion tumours have …
[HTML][HTML] Concurrent driver gene mutations as negative predictive factors in epidermal growth factor receptor-positive non-small cell lung cancer
M Chen, Y Xu, J Zhao, W Zhong, L Zhang, Y Bi… - …, 2019 - thelancet.com
… -cell lung cancer to gefitinib. … response to treatment and epidermal growth factor receptor
tyrosine kinase inhibitors in patients with EGFR-mutant advanced non-small cell lung cancer. …
tyrosine kinase inhibitors in patients with EGFR-mutant advanced non-small cell lung cancer. …
[HTML][HTML] EGFR exon 20 insertion in metastatic non-small-cell lung cancer: survival and clinical efficacy of EGFR tyrosine-kinase inhibitor and chemotherapy
S Chelabi, X Mignard, K Leroy, I Monnet, S Brosseau… - Cancers, 2021 - mdpi.com
… There was no significant difference in the tumor response or … Epidermal growth factor
receptor (EGFR) mutations, mainly … to standard TKIs (erlotinib, gefitinib, afatinib), and their …
receptor (EGFR) mutations, mainly … to standard TKIs (erlotinib, gefitinib, afatinib), and their …