… A model of the generation of p52 from p100. In the resting cells, p100 forms high molecular
… while RelA is not inducibility expressed, it induces the expression of p100/p52 and RelB. This …

… dimer generated by a high and a small monomer (ie, RelA/p52, … , receptor activator of NF-κB
ligand (RANKL), lymphotoxin β (LTβ… reduces the LPS- and β-amyloid-induced glycolysis and …

… (while p50 and p52 homo- and hetero-dimers repress NF-κB-… TNF family receptor (BAFFR),
lymphotoxin β-receptor (LTβR)… an abrogation of the LPS-induced proinflammatory response […

… Although best known as critical regulators of the inflammatory response, the NFκB family
of transcription factors are also activated by cellular stresses such as hypoxia, DNA damage …

… repeats of the C-terminal, and which cause overexpression of p52 again highlights the …
unlike the other subunits of NFκB. Instead, it forms heterodimers with p50 and p52, the highest …

… BAFF-R B cell activating factor of the TNF family, LTβR lymphotoxin-β-receptor, NEMO NF-κB
essential modulator, NIK NF-κB inducing kinase, TAB TAK-binding protein, TAK1 TGF-β-…

… phosphorylation of p52/p100 which … induce classical NF-κB pathway are TNF and LPS, and
both classical and non-classical NF-κB pathway can be induced by the activated lymphotoxin …

… We addressed the mechanism of NF-κB dimer formation in the … that very little p52:p52
homodimer is generated in the … other p52 containing dimers (p52:RelA, p52:cRel, and p52:…

… receptors, such as TNFR2, lymphotoxin-β receptor (LT-βR), B cell … TRAF degradation is
critical for the activation of NF-κB-inducing … processing to active p52 subunit. As a result, RelB/…

… In the canonical pathway, the K63-Ub chain generated by TRAF6 … the fetal lymphotoxin
producer cells. RANK activates the TRAF6-… The resulting p52/RelB heterodimer then induces the …