[HTML][HTML] DNA methylation data by sequencing: experimental approaches and recommendations for tools and pipelines for data analysis

I Rauluseviciute, F Drabløs, MB Rye - Clinical epigenetics, 2019 - Springer
… The most frequently described tools for data normalization are BATMAN and MEDME or
the MEDIPS pipeline that combines both [3, 43]. MeQA and MeDUSA are the pipelines that …

[HTML][HTML] Computational challenges in detection of cancer using cell-free DNA methylation

M Sharma, RK Verma, S Kumar, V Kumar - Computational and Structural …, 2022 - Elsevier
… of experimental protocols, and analysis procedures. In our review, besides exploring the cfDNA
methylation origin and analysis techniques, we … MEDME Provides both relative as well as …

[HTML][HTML] Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance …

K Takasawa, K Asada, S Kaneko, K Shiraishi… - Experimental & …, 2024 - nature.com
… comparative analysis within a … novel method for DNA methylation analysis, namely,
methPLIER, which enables interdataset comparative analyses. methPLIER combines Pathway Level

CoMeBack: DNA methylation array data analysis for co-methylated regions

E Gatev, N Gladish, S Mostafavi, MS Kobor - Bioinformatics, 2020 - academic.oup.com
… a method named Co-Methylation with genomic CpG Background (CoMeBack) that estimates
DNA co-methylation, … CoMeBack outputs co-methylated regions (CMRs), spanning sets of …

COMPUTATIONAL ANALYSIS OF THE PHENOTYPIC SIGNIFICANCE OF INDIVIDUAL DNA METHYLATION SITES

BA Alharbi - 2021 - search.proquest.com
… This sequence, a well-known regulatory consensus sequence indicating methylation level
in these two sites, plays a primary part in regulating the expression level of SERPINA1 in …

Detecting neuroendocrine prostate cancer through tissue-informed cell-free DNA methylation analysis

JE Berchuck, SC Baca, HM McClure, K Korthauer… - Clinical Cancer …, 2022 - AACR
… We believe that the methods presented herein will help facilitate … DNA methylation is present
across tumor types with several clinically actionable subtypes harboring distinct methylation

CanMethdb: a database for genome-wide DNA methylation annotation in cancers

J Zhao, F Qian, X Li, Z Yu, J Zhu, R Yu, Y Zhao… - …, 2023 - academic.oup.com
… mean DNA methylation level between normal and tumor samples ≥0.1. If the methylation
level … We used this method to define methylation status for the paired CpGs in 20 cancer types (…

An unbiased predictive model to detect DNA methylation propensity of CpG Islands in the human genome

D Yalcin, HH Otu - Current Bioinformatics, 2021 - ingentaconnect.com
MEME model described in this paper, we also built a biased MEME model to reproduce the
Feltus et al. methodology … that are experimentally validated as methylation prone or resistant …

Bioinformatics of Genome-wide DNA Methylation Studies

N Sharma, AN Singh - Bioinformatics and Human Genomics …, 2021 - taylorfrancis.com
… For post-experimental analysis for restriction enzyme and enzyme-based approaches …
MEDME: An experimental and analytical methodology for the estimation of DNA methylation levels

[HTML][HTML] A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates

H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
… of DNA methylation associated with X-… DNA methylation, we show that the silencing of
germline genes and endogenous retroviruses (ERVs) are conserved functions of DNA methylation