[HTML][HTML] … randomized clinical trial of endovascular treatment of acute ischemic stroke in The Netherlands for late arrivals: study protocol for a randomized controlled trial

…, RJ van Oostenbrugge, MR CLEAN-LATE investigators - Trials, 2021 - Springer
Background Endovascular therapy (EVT) for acute ischemic stroke due to proximal
occlusion of the anterior intracranial circulation, started within 6 h from symptom onset, has
been proven safe and effective. Recently, EVT has been proven effective beyond the 6-h
time window in a highly selected population using CT perfusion or MR diffusion.
Unfortunately, these imaging modalities are not available in every hospital, and strict
selection criteria might exclude patients who could still benefit from EVT. The presence of …

[HTML][HTML] Multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke. The effect of periprocedural medication: acetylsalicylic acid …

V Chalos, RA van de Graaf, B Roozenbeek… - Trials, 2020 - Springer
Background Despite evidence of a quite large beneficial effect of endovascular treatment
(EVT) for ischemic stroke caused by anterior circulation large vessel occlusion, many
patients do not recover even after complete recanalization. To some extent, this may be
attributable to incomplete microvascular reperfusion, which can possibly be improved by
antiplatelet agents and heparin. It is unknown whether periprocedural antithrombotic
medication in patients treated with EVT improves functional outcome. The aim of this study is …
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