… During intramembranous ossification, osteoblasts differentiate directly within the
mesenchymal tissue. Examples of bones that form through intramembranous ossification during …

… -regulated kinase (ERK) MAPK pathway plays a vital role in osteoblastic differentiation.
Naringin has been shown to increase Erk expression and phosphorylation in osteoblasts, …

Full article: Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have
collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis Skip …

… Mangiferin (xanthone originally extracted from mango tree) attenuates ovariectomy-induced
osteoporosis in rats [149] and promotes osteoblast differentiation through the increased …

… oxidative damage, we examined the effect of Bach1 inhibition or overexpression on
osteoblast differentiation in response to H 2 O 2 exposure. The results demonstrated that H 2 O 2 …

… to impaired bone homeostasis caused by reduced osteoblast differentiation (21). Therefore,
it is speculated that Mir-182 of osteoclast-derived exosomes can promote bone resorption …

… osteoclast differentiation. Finally, our results reveal that Tan IIA suppresses osteoclast
differentiation via LDHC-mediated ROS generation in osteoclasts. Tan IIA can thus be regarded as …

… to induce preosteoblast development into osteoblasts (10). Cocoa antioxidants are …
osteoblast differentiation so that bone mineralization happens fast and the efficacy of osteoclasts is …

α-Mangostin (aMan) and Paeonol (Pae) have shown anticancer and anti-inflammatory
properties. However, these two natural compounds have no clinical value because of their low …

… nuclear accumulation of Nrf2 after mangiferin treatment. Moreover, NQO1, … osteoclast
differentiation takes place [109]. The activity of osteoblasts and osteoclasts is positively regulated …