[HTML][HTML] Polarized macrophages in periodontitis: characteristics, function, and molecular signaling
X Sun, J Gao, X Meng, X Lu, L Zhang… - Frontiers in …, 2021 - frontiersin.org
… (162) found that inhibition of NF-κB and JAK1/STAT1/3 signaling pathway is the main
mechanism by which Mangiferin ameliorates experimental periodontitis in mice. Efforts to maintain …
mechanism by which Mangiferin ameliorates experimental periodontitis in mice. Efforts to maintain …
[HTML][HTML] Advances in the Pathogenesis of Steroid-Associated Osteonecrosis of the Femoral Head
J Zhang, J Cao, Y Liu, H Zhao - Biomolecules, 2024 - mdpi.com
… Conversely, miR-141 can boost osteoblast activity and hinder osteoclasts through the TGF-…
can stimulate osteoblast differentiation. MiR-122 may affect SANFH by regulating the SPRY2 …
can stimulate osteoblast differentiation. MiR-122 may affect SANFH by regulating the SPRY2 …
[HTML][HTML] Integrated phytochemistry and network pharmacology analysis to reveal effective substances and mechanisms of Bushen Quhan Zhiwang decoction in the …
LB Zhang, Y Yan, R Ma, DX Li, WF Yin, QW Tao… - Journal of …, 2024 - Elsevier
… BQZD treatment attenuated paw swelling and the arthritis index; suppressed synovial
hyperplasia, bone destruction, and osteoclast differentiation; and inhibited the levels of TNF-α, IL-…
hyperplasia, bone destruction, and osteoclast differentiation; and inhibited the levels of TNF-α, IL-…
[HTML][HTML] A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia
T Morikawa, K Ninomiya, G Tanabe, H Matsuda… - Journal of natural …, 2021 - Springer
During our studies characterizing functional substances from food resources for the prevention
and treatment of lifestyle-related diseases, we isolated the active constituents, salacinol (1…
and treatment of lifestyle-related diseases, we isolated the active constituents, salacinol (1…
[HTML][HTML] Bioactive molecules against rheumatoid arthritis by suppressing pyroptosis
Q Zhou, T Li, G Fang, Y Pang, X Wang - Pharmaceuticals, 2023 - mdpi.com
Rheumatoid arthritis is an inflammatory disease, and pyroptosis is a form of death associated
with an inflammatory response. Pyroptosis, which occurs in synovial and osteoblastic cells, …
with an inflammatory response. Pyroptosis, which occurs in synovial and osteoblastic cells, …
[HTML][HTML] Small molecule Wnt pathway modulators from natural sources: history, state of the art and perspectives
A Blagodatski, A Klimenko, L Jia, VL Katanaev - Cells, 2020 - mdpi.com
… branches as active in stimulating osteoblast differentiation and enhancing murine calvarial …
accumulation of β-catenin in murine primary osteoblasts [66]. Extracts of the widespread plant …
accumulation of β-catenin in murine primary osteoblasts [66]. Extracts of the widespread plant …
Fusion and hemagglutinin proteins of canine distemper virus promote osteoclast formation through NF-κB dependent and independent mechanisms
W Wang, W Feng, D Li, S Liu, Y Gao, Z Zhao… - Experimental Cell …, 2019 - Elsevier
… that CDV positively regulates RANKL-induced osteoclastic differentiation and function. … It
demonstrates that CDV and F + H positively regulate RANKL-induced osteoclastogenesis at …
demonstrates that CDV and F + H positively regulate RANKL-induced osteoclastogenesis at …
[HTML][HTML] Pyroptosis in Skeleton Diseases: A Potential Therapeutic Target Based on Inflammatory Cell Death
… exacerbates osteoblast death and osteoclast formation, … shown to support osteoblast
differentiation and osteogenesis, … chondrocyte pyroptosis is positively regulated by upstream NF-…
differentiation and osteogenesis, … chondrocyte pyroptosis is positively regulated by upstream NF-…
Autophagy, SMAD-1, and apoptotic pathways are correlated with L-carnitine protective effect against dexamethasone-induced osteoporosis in Wistar rats
S Ahmed, D Elbahy - Records of Pharmaceutical and Biomedical …, 2022 - journals.ekb.eg
… The cofactor in fatty acid beta-oxidation, L-carnitine (LC), has been found to regulate osteoblast
activity. Therefore, this work aimed to investigate the potential defensive properties of LC …
activity. Therefore, this work aimed to investigate the potential defensive properties of LC …