… Additionally, GLP-1 also activates the Wnt pathway, promoting osteoblast differentiation from
mesenchymal stem cells and maturation, and suppresses sclerostin expression and activity…

… For instance, the xanthones, mangiferin and isomangiferin, and hespiridin that are present in
both … It is thus difficult to speculate what the effect of mangiferin would be on the ER subtype …

… abnormal osteoblast and osteoclast differentiation impair the bone homeostasis that is
consistent with our enriched results. As one of the monocyte-macrophage systems, osteoclasts …

… positively regulates the activation of NF-κB. This vicious cycle will permanently amplify the
inflammatory response of RA, leading to severe synovial hyperplasia, angiogenesis, cartilage …

… et Mey)] showed an important protective role in Cd-exposed mice, as it positively regulated
… Mangiferin (MGN) is a glucosylxanthone particularly abundant in the leaves and edible …

… The receptor activator of kappa-B (RANK) is a crucial factor affecting the balance between
osteoblasts and osteoclasts. It directly induces osteoclast differentiation and maturation, …

… Osteoblasts, osteoclasts, and hematopoietic precursors that accompany vascular invasion …
bone tissue engineering by regulating stem cell proliferation and differentiation. Among these …

… Mangiferin reduced BGL and increased serum insulin at a dose of 200 mg/kg in diabetic …
activation that has been shown to induce osteoblastic differentiation [421]. Moreover, icariin and …

The aim of the current study was to to investigate the influence of cornelian cherry (Cornus
mas L.; CM) extract on ovariectomy-induced metabolic changes including bone loss, obesity …

… Although the biologic agents targeted against TNFα and IL-1 receptors were successful
in suppressing inflammatory reactions in RA, 60% of individuals had some evidence of …