Advances in local therapy for glioblastoma—taking the fight to the tumour
TS van Solinge, L Nieland, EA Chiocca… - Nature Reviews …, 2022 - nature.com
… In this Review, we discuss the latest developments in local therapy for glioblastoma,
focusing on recent preclinical and clinical trials. The approaches that we discuss include novel …
focusing on recent preclinical and clinical trials. The approaches that we discuss include novel …
[HTML][HTML] Artificial intelligence in the management of glioma: era of personalized medicine
… Classically, in glioma clinical trials, the most common biomarkers are the status of MGMT …
markers which can predict the treatment response to a particular treatment. This would help …
markers which can predict the treatment response to a particular treatment. This would help …
[HTML][HTML] The evolution of alternative splicing in glioblastoma under therapy
… Thus, mapping AS is of high clinical importance, to identify novel … To determine the effect
of SRSF5 overexpression (OE), we transfected the patient-derived glioma cell line U87 with …
of SRSF5 overexpression (OE), we transfected the patient-derived glioma cell line U87 with …
[HTML][HTML] New directions in the therapy of glioblastoma
K Szklener, M Mazurek, M Wieteska, M Wacławska… - Cancers, 2022 - mdpi.com
… associated with satisfactory treatment responses. Therefore, … ), and cortical/subcortical
mapping techniques may be used [… was used in trials in patients with recurrent malignant glioma. …
mapping techniques may be used [… was used in trials in patients with recurrent malignant glioma. …
[HTML][HTML] A vaccine targeting mutant IDH1 in newly diagnosed glioma
… immune responses were observed in 93.3% of patients … Patients with immune responses
showed a two-year progression-free rate of 0.82. Two patients without an immune response …
showed a two-year progression-free rate of 0.82. Two patients without an immune response …
Current approaches and challenges in the molecular therapeutic targeting of glioblastoma
J Mooney, JD Bernstock, A Ilyas, A Ibrahim… - World neurosurgery, 2019 - Elsevier
… Researchers are testing the safety/dosing of the NSC-based therapy in combination with
radiation and chemotherapy for patients with newly diagnosed malignant gliomas. The study …
radiation and chemotherapy for patients with newly diagnosed malignant gliomas. The study …
[HTML][HTML] Coding of glioblastoma progression and therapy resistance through long noncoding RNAs
A Zottel, N Šamec, A Videtič Paska, I Jovčevska - Cancers, 2020 - mdpi.com
… , therapeutic targets that can contribute to prolonged survival and improved quality of life
for patients with glioblastoma. … from grade I (benign) to grade IV (malignant glioblastoma). …
for patients with glioblastoma. … from grade I (benign) to grade IV (malignant glioblastoma). …
Diagnostic performance of multiparametric MRI in the evaluation of treatment response in glioma patients at 3T
J Liu, C Li, Y Chen, X Lv, Y Lv, J Zhou… - Journal of Magnetic …, 2020 - Wiley Online Library
… , rCBF (e), and APTw (f) maps. Multiparametric MR indices were … of a representative patient
confirmed as treatment effects. Briefly… displays hyperintense in the ADC map. Meanwhile, the …
confirmed as treatment effects. Briefly… displays hyperintense in the ADC map. Meanwhile, the …
[HTML][HTML] Assessment of glioblastoma response in the era of bevacizumab: longstanding and emergent challenges in the imaging evaluation of pseudoresponse
OD Arevalo, C Soto, P Rabiei, A Kamali… - Frontiers in …, 2019 - frontiersin.org
… determination of treatment responses of malignant brain tumors… the response assessment
of supratentorial malignant gliomas … of BEV (cellularity and cell replication); to identify and map …
of supratentorial malignant gliomas … of BEV (cellularity and cell replication); to identify and map …
Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities
… g, Enrichment map network of statistically significant lipid … subtypes and predicted the
therapeutic response of MTC PDCs to … testing the effect of OXPHOS inhibitors in patients with …
therapeutic response of MTC PDCs to … testing the effect of OXPHOS inhibitors in patients with …