[HTML][HTML] Machine learning and glioma imaging biomarkers

TC Booth, M Williams, A Luis, J Cardoso, K Ashkan… - Clinical radiology, 2020 - Elsevier
… the time that patients first present with a brain tumour. Differentiating a treatment response
from a post-treatment-related effect using … (grades 3 and 4), which are the malignant gliomas. …

Myeloid cells in glioblastoma microenvironment

A De Leo, A Ugolini, F Veglia - Cells, 2020 - mdpi.com
… ; these cells are critical regulators of immune and therapeutic responses to GBM. Here, we
will … to promote radiotherapy for glioma treatment induced cytotoxicity to glioma cells under …

Functional alterations in cortical processing of speech in glioma-infiltrated cortex

AA Aabedi, B Lipkin, J Kaur… - Proceedings of the …, 2021 - National Acad Sciences
… As such, we recorded ECoG activity in 12 nonaphasic patients with malignant gliomas on
the … To do so, we performed cortical language mapping in all 12 participants using direct …

Current landscape and emerging fields of PET imaging in patients with brain tumors

JM Werner, P Lohmann, GR Fink, KJ Langen… - Molecules, 2020 - mdpi.com
… ), the assessment of treatment response to systemic treatment options such as … response
to antiangiogenic therapy with bevacizumab in patients with recurrent malignant glioma

A STAT3-based gene signature stratifies glioma patients for targeted therapy

MSY Tan, E Sandanaraj, YK Chong, SW Lim… - Nature …, 2019 - nature.com
… This may account for the frequently observed inter-patient variability to treatment response.
Indeed, … The premise of our hypothesis rests in being able to map these modules in clinical …

[HTML][HTML] Immune checkpoint targeted therapy in glioma: status and hopes

Y Qi, B Liu, Q Sun, X Xiong, Q Chen - Frontiers in immunology, 2020 - frontiersin.org
malignant glioma remain unknown, as the low response and persistence of treatments in
glioma … Given this, individualized treatment and real-time monitoring of treatment response are …

[HTML][HTML] Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma

EF Simonds, ED Lu, O Badillo, S Karimi… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
patients, metacluster frequencies for each primary tumor were fed into the t-stochastic neighbor
embedding (t-SNE) dimensionality reduction algorithm to produce a map of … The glioma

Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma

SC Mack, I Singh, X Wang, R Hirsch, Q Wu… - Journal of Experimental …, 2019 - rupress.org
… To delineate genes important for defining and maintaining the GSC state, we mapped SE
loci across a large panel of patient-derived GSC cultures. Our analysis revealed 8,533 distinct …

Decipher the glioblastoma microenvironment: the first milestone for new groundbreaking therapeutic strategies

GN Fanelli, D Grassini, V Ortenzi, F Pasqualetti… - Genes, 2021 - mdpi.com
Malignant gliomas typically contain both neoplastic cells and … ; and (iii) glioblastoma NOS,
for which full IDH evaluation … differ in prognosis and therapy response. Primary glioblastomas …

Glioblastoma: clinical presentation, diagnosis, and management

C McKinnon, M Nandhabalan, SA Murray, P Plaha - Bmj, 2021 - bmj.com
… tissue, and cortical mapping in awake patients.Tumour specimens … glioblastoma diagnosis
and monitor treatment response? … neurocognitive dysfunction in patients with diffuse glioma: a …