Calcium promotes vascular smooth muscle cell phenotypic switching in Marfan syndrome
Y Yang, E Xie, Y Liu, Z Peng, C Yu, K Hua… - … and Biophysical Research …, 2023 - Elsevier
… Syyong et al. found that the frequency of calcium waves is reduced in the second-order
branches of the mesenteric artery of MFS mice (Fbn1 C1039G/+ ) at 24 weeks of age [26]. A …
branches of the mesenteric artery of MFS mice (Fbn1 C1039G/+ ) at 24 weeks of age [26]. A …
Vascular Smooth Muscle Cell Mechanobiology in Aortopathies
RJ Wiener - 2023 - search.proquest.com
… the aorta, specifically Marfan syndrome, we studied whether … to increased stiffness, and
impaired vasodilation. In aging, changes … and Vasoconstriction in Murine Mesenteric Resistance …
impaired vasodilation. In aging, changes … and Vasoconstriction in Murine Mesenteric Resistance …
[HTML][HTML] Activation of Cav1. 2 and BKCa is involved in the downregulation of caffeine-induced contraction in mice mesenteric arteries
DCG Garcia, MJ Lopes, UC Mbiakop, VS Lemos… - Life sciences, 2019 - Elsevier
… 1.2 increased the TC while reduced the i Ca 2+ signal. Similar … of VSMCs contraction in
resistance arteries. The evidence of … when we compare Ca 2+ -sparks or Ca 2+ -waves [12]. In …
resistance arteries. The evidence of … when we compare Ca 2+ -sparks or Ca 2+ -waves [12]. In …
Aortic stiffness in L-NAME treated C57Bl/6 mice displays a shift from early endothelial dysfunction to late-term vascular smooth muscle cell dysfunction
S De Moudt, JO Hendrickx, C Neutel… - Frontiers in …, 2022 - frontiersin.org
… control mice, indicating that L-NAME treatment increases the … In this context, insulin-induced
vasodilation may represent a … and resistance arteries in L-NAME induced cardiovascular …
vasodilation may represent a … and resistance arteries in L-NAME induced cardiovascular …
Intrinsic Mechanics of Human Stem Cell Derived Aortic Smooth Muscle Cells Support a Developmental Basis for Aneurysm Localization in Marfan Syndrome
RJ Wiener, H Orins, KD Costa - bioRxiv, 2023 - biorxiv.org
… Marfan Syndrome Decreases Ca2+ Wave Frequency and Vasoconstriction in Murine Mesenteric
Resistance Arteries without Changing Underlying Mechanisms. JVR 48, 150–162 (2011…
Resistance Arteries without Changing Underlying Mechanisms. JVR 48, 150–162 (2011…
The onset of cardiovascular disease in mice: an image-based, computational-experimental approach
L Aslanidou - 2019 - infoscience.epfl.ch
… Rp is peripheral resistance (summed resistance of peripheral beds)… As we saw, in Marfan
syndrome the defective synthesis of … rat mesenteric arteries to measure their vasoconstriction or …
syndrome the defective synthesis of … rat mesenteric arteries to measure their vasoconstriction or …
Vascular smooth muscle cell PIEZO-1 in Abdominal Aortic Aneurysm formation
MA Waduud - 2023 - etheses.whiterose.ac.uk
… this work I had never handled a mouse or any animal, for that … through vasoconstriction
and vasodilation determined by … physiological decreases in peripheral resistance that occurs …
and vasodilation determined by … physiological decreases in peripheral resistance that occurs …
Central artery stiffness and thoracic aortopathy
JD Humphrey, G Tellides - American Journal of Physiology …, 2019 - journals.physiology.org
… We consider Marfan syndrome as an illustrative aortopathy … E57K/E57K mice but no effect
on muscular (renal, mesenteric, or … vasoconstriction can reduce wall stress overall (by reducing …
on muscular (renal, mesenteric, or … vasoconstriction can reduce wall stress overall (by reducing …
Study of molecular causes underlying Williams-Beuren syndrome phenotype through the development of novel therapeutic approaches
P Ortiz Romero - 2019 - tdx.cat
… We have used a WBS mouse model carrying a heterozygous … of Ca2+ from intracellular
stores and the entry of Ca2+ from … triggering the response to vasoconstrictor signals by virtue of …
stores and the entry of Ca2+ from … triggering the response to vasoconstrictor signals by virtue of …
Investigating the Impact of Endothelial Dysfunction and Aging on Vascular Remodeling Using Mouse Models
L Du - 2022 - search.proquest.com
… mesenteric arteries, located distally from the heart, which primarily constitute the vascular
resistance … resulting from tonic sympathetic neural input and vasoconstrictors, and vasodilation …
resistance … resulting from tonic sympathetic neural input and vasoconstrictors, and vasodilation …