[HTML][HTML] Germ-free mice exhibit mast cells with impaired functionality and gut homing and do not develop food allergy

M Schwarzer, P Hermanova, D Srutkova… - Frontiers in …, 2019 - frontiersin.org
… : Mucosal mast cells (MC) are key players in IgE-mediated food … 48/80, which has been
used to induce MC degranulation … of the 48/80 induced edema in footpad of CV mice and this …

[HTML][HTML] Ayurvedic herbal formulations Haridra Khanda and Manjisthadi Kwath (Brihat) in the management of allergic rhinitis: A pharmacological study

R Bhowmik, MA Shaharyar, MM Kanakal, A Sarkar… - Heliyon, 2024 - cell.com
… The compound 48/80 (intracutaneous) challenged mice … acute anaphylaxis and the latter
mast cell degranulation. For both models, … In the histamine and compound 48/80 induced model …

Proteinase-Activated Receptors in Itch and Pain

MS Lee, EA Lerner - Itch and Pain: Similarities, Interactions, and …, 2020 - books.google.com
… in PAR-mediated scratching behavior in mice have been … mouse mast cells by tryptase
elicits scratching behavior that does not occur either in mast cell–deficient mice or when the mice

Therapeutic potential of bromhexine for acute itch in mice: Involvement of TMPRSS2 and kynurenine pathway

A Afrooghe, M Babaei, M Shayan, E Ahmadi… - International …, 2023 - Elsevier
mast cell degranulation and, thus, increasing histamine release. Bromhexine mediates its
… bromhexine is able to alleviate C 48/80-induced acute itch in mice. According to our findings…

[HTML][HTML] Histamine induced high mobility group box-1 release from vascular endothelial cells through H1 receptor

S Gao, K Liu, W Ku, D Wang, H Wake, H Qiao… - Frontiers in …, 2022 - frontiersin.org
… in vivo by a liberator of histamine from mast cells may be mediated in part by HMGB1.
These … injection of compound 48/80, a mast cell stimulator, in rats. The compound 48/80-induced

[HTML][HTML] Immune mechanisms in vulvodynia: key roles for mast cells and fibroblasts

E Tonc, GK Omwanda, KA Tovar… - Frontiers in Cellular …, 2023 - frontiersin.org
… labial skin of previously sensitized mice resulted in mast cell accumulation and remarkably
… of how immune mechanisms mediated by mast cells, fibroblasts and other cells contribute to …

[HTML][HTML] Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi

E Bencosme-Cuevas, TK Kim, TT Nguyen… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
… /c mice paw edema but did not significantly alter the mast cell … (A) Twelve retired female
BALB/c mice, divided into four … with saline, compound 48/80 (1 µg of mast cell degranulator), …

[HTML][HTML] Immune actions on the peripheral nervous system in pain

JA Liu, J Yu, CW Cheung - International journal of molecular sciences, 2021 - mdpi.com
compound 48/80 induced degranulation of mast cells and caused … -mediated vasodilation
and mast cell degranulation were found to be key mechanisms in driving migraine in a mouse

Rhipicephalus microplus serpins interfere with host immune responses by specifically modulating mast cells and lymphocytes

ML Coutinho, B Bizzarro, L Tirloni, M Berger… - Ticks and tick-borne …, 2020 - Elsevier
… in cells involved in innate/inflammatory (mast cells and macrophages) and adaptive (T
cells) immunity. RmS-3 modulated mast cells due to its inhibitory activity on peritoneal rat …

Evaluation of anti-inflammatory activity and molecular docking study of new aza-bicyclic isoxazoline acylhydrazone derivatives

FVB Mota, MS de Araújo Neta, E de Souza Franco… - …, 2019 - pubs.rsc.org
… as reduce leukocyte migration and inhibit mast cell degranulation. … The intraplantar injection
of compound 48/80 induced the … , mediating adhesion, chemotaxis, and degranulation. This …