… mice led to thermal and mechanical plantar hyperalgesia that is blocked by a mast cell stabilizer
drug and in mast cell-deficient mice [… compound 48/80 mast cell degranulation reduces …

… from classic IgE-mediated degranulation and has emerged as … In our mouse studies,
Mrgprb10 was found to be de novo … in gut mast cells and their role as novel mast cell activation …

… -mediated mast cell degranulation differs from the canonical FcR-dependent activation and
is characterized by a fast and local degranulation … when mice were deficient in mast cells or …

… In conclusion, our results identify intercellular signaling mechanisms between mast cells,
enteric glia, and neurons that are mediated by histamine and altered by early-life stress. Higher …

… Compound 48/80-induced acute pruritus is primarily associated with mast-cell degranulation
… In contrast, STING-mediated IFN-I response is revealed to be protective against depression-…

… on MRGPRX2-mediated mast cell degranulation 47,114-123. It … expressing mast cells were
not present in Mrgprd-deficient mice… Roxithromycin inhibits compound 48/80-induced pseudo…

… of the neuronal circuits that mediate interoception, our … ) or compound 48/80 induced
non-histaminergic itch that was impaired in MrgprB2-deficient animals or mice lacking mast cells [62]…

… light on neuro-immune interactions mediating the development, … Inhibition of mast cell
degranulation leads to a decrease in … in female mice and absent in T-cell-deficient mice. Adoptive …

… Mice were euthanized after 4 h … compound 48/80-induced paw edema mediate an increase
in vascular permeability, which is dependent on tissue osmolarity and mast cell degranulation…

… showed that compound 48/80 induced persistent nociceptive firing in the trigeminal nerve
… CGRP is multifunctional peptide mediating pain as well as a growth factor for primitive cells, …