[HTML][HTML] Label-free assessment of pre-implantation embryo quality by the Fluorescence Lifetime Imaging Microscopy (FLIM)-phasor approach

N Ma, NR Mochel, PD Pham, TY Yoo, KWY Cho… - Scientific Reports, 2019 - nature.com
… To test this hypothesis, we first measured the metabolic activity of intracellular NADH 26 . …
the embryos predicted to be healthy in positive values (EVI < 0, in blue), and embryos predicted

Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment

T Sanchez, M Venturas, SA Aghvami… - Human …, 2019 - academic.oup.com
… to determine if metabolic imaging is sensitive enough to also measure the changes in embryo
metabolism … that metabolic imaging is a highly sensitive assay for measuring changes in …

Metabolic remodelling during early mouse embryo development

J Zhao, K Yao, H Yu, L Zhang, Y Xu, L Chen, Z Sun… - … Metabolism, 2021 - nature.com
metabolic remodelling during pre-implantation embryo … to directly measure metabolite
abundance in embryos. Due to … 5a), and differential genetic deletion sensitivity was predicted

Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes

P Hernández-Vargas, M Muñoz… - Human reproduction …, 2020 - academic.oup.com
… involved in the embryo–uterine interaction. More reliable biological markers to predict
embryo and uterine reproductive competence are needed to improve pregnancy outcomes. …

The mitochondrial DNA content of cumulus cells may help predict embryo implantation

A Taugourdeau, V Desquiret-Dumas, JF Hamel… - Journal of Assisted …, 2019 - Springer
… to embryonic quality [8]; here, we show that for embryos of equivalent quality, this amount of
mtDNA is related to embryonic … Moreover, the mitochondrial mass is related to the metabolic

Oxidative stress markers in the follicular fluid of patients with polycystic ovary syndrome correlate with a decrease in embryo quality

Y Liu, Z Yu, S Zhao, L Cheng, Y Man, X Gao… - Journal of Assisted …, 2021 - Springer
… It is also associated with long-term metabolic disorders [9, 10]… In this study, we simultaneously
measured representative OS … to measure and have good ability to predict embryo quality, …

Deep learning as a predictive tool for fetal heart pregnancy following time-lapse incubation and blastocyst transfer

D Tran, S Cooke, PJ Illingworth… - Human …, 2019 - academic.oup.com
… of predicting the probability of pregnancy with FH given time-lapse video sequence. The
predictive power of the model was measured using … physiology, such as metabolic activity and …

[HTML][HTML] The pre-hatching bovine embryo transforms the uterine luminal metabolite composition in vivo

M Sponchiado, AM Gonella-Diaza, CC Rocha… - Scientific reports, 2019 - nature.com
… More specifically, we aimed to measure the absolute … to determine, within the specific
classes of metabolites … The pre-hatching embryo modulates the eicosanoid metabolism in the …

[HTML][HTML] How can we improve embryo production and pregnancy outcomes of Holstein embryos produced in vitro? (12 years of practical results at a California dairy …

DGB Demetrio, E Benedetti, CGB Demetrio… - Animal …, 2020 - SciELO Brasil
… link between maternal metabolism and oocyte quality: a … be present and an estimate of the
final embryo production was … the oocyte and embryo, we adopted several measures based on …

[HTML][HTML] Application of extracellular flux analysis for determining mitochondrial function in mammalian oocytes and early embryos

B Muller, N Lewis, T Adeniyi, HJ Leese, DR Brison… - Scientific Reports, 2019 - nature.com
… a further 5 days to determine whether the distinct groups … embryo metabolism, the assays
used are technically complex and require dedicated equipment sensitive enough to measure