… integrity and quality control mechanisms is associated to numerous disorders, ranging from
… to neuronal cell death and is a hallmark of Alzheimer disease. When expressed in yeast, …

… ) with the proteasome inhibitor MG132 in HCT116 colon cancer cells. Through proteomic
analyses, we uncover the specific molecular mechanism by which p97 inhibition is distinct from …

… The TAG accumulation and regulation of OLE1 counter Cd-induced cell death in yeast (Fang …
Ubx2 is a bridging factor and is involved in ERAD as a part of the quality control mechanism…

… In contrast, it is commonly assumed that dying yeast cells (maybe owing to the fungal cell …
apoptotic bodies but can undergo a biphasic cell death execution mechanism, with apoptotic …

… Since Rac is an important player during apoptotic cell death in other cell types, we asked
whether a similar mechanism might be involved in Rho5-mediated cell death in …

… cellular degradative mechanisms modulate Tau aggregation. During aging and
neurodegenerative disorders, the cellular … Tau in preventing apoptotic cell death by mitigating ER …

… Although we do not yet fully understand the detailed mechanism of TER94/VCP interaction
with … approaches will be necessary to investigate the underlying mechanisms involved. …

… underlying mechanisms of ADSCs in bladder tumor (BT) cells. SV-HUC, T24, and EJ …
Apoptosis and cell cycle arrest are two different mechanisms involved in the induction of cell death (…

… pathways by nanoplastics, which might lead to programmed cell death. Similar findings of
… , Mechanisms of Cdc48/VCP-mediated cell death—from yeast apoptosis to human disease. …

… Studies have shown that ML240 and ML241 have different mechanisms of action. Among
these p97 inhibitors, as the first-generation selective inhibitor CB-5083, has a highly selective …