Melatonin protects against chronic stress-induced oxidative meiotic defects in mice MII oocytes by regulating SIRT1
Y Guo, J Sun, S Bu, B Li, Q Zhang, Q Wang, D Lai - Cell Cycle, 2020 - Taylor & Francis
… and mitochondria malfunction by regulating SIRT1 and … production in oocytes could be
attenuated by melatonin. … that melatonin administration induced the expression of SIRT1 …
attenuated by melatonin. … that melatonin administration induced the expression of SIRT1 …
[HTML][HTML] Insufficiency of melatonin in follicular fluid is a reversible cause for advanced maternal age-related aneuploidy in oocytes
M Zhang, Y Lu, Y Chen, Y Zhang, B Xiong - Redox biology, 2020 - Elsevier
… We revealed that melatonin treatment effectively attenuated … Sirt1 was considerably
down-regulated in the aged oocytes but up-… Sirt1 expression in the melatonin-administered …
down-regulated in the aged oocytes but up-… Sirt1 expression in the melatonin-administered …
Melatonin promotes parthenogenetic development of vitrified-warmed mouse MII oocytes, potentially by reducing oxidative stress through SIRT1
T Lv, B Cao, J Qin, Y Wei, B Pan, J Ye, G Zhou - Theriogenology, 2023 - Elsevier
… post-ovulatory aging oocytes, ROS level is increased while SIRT1 expression is down-regulated…
overexpression of SIRT1 can reduce aging-induced mitochondrial dysfunction and ROS …
overexpression of SIRT1 can reduce aging-induced mitochondrial dysfunction and ROS …
Therapeutic effect of melatonin in premature ovarian insufficiency: hippo pathway is involved
MK Qi, TC Sun, LY Yang, JL He, YM Guo… - Oxidative medicine …, 2022 - Wiley Online Library
… role in post-ovulatory oocyte senescence by controlling the … MT attenuates sepsis-induced
brain damage through SIRT1 … MT treatment significantly increases SIRT1 expression, …
brain damage through SIRT1 … MT treatment significantly increases SIRT1 expression, …
Melatonin attenuates oxidative stress-induced apoptosis of bovine ovarian granulosa cells by promoting mitophagy via SIRT1/FoxO1 signaling pathway
G Xu, Y Dong, Z Wang, H Ding, J Wang, J Zhao… - International Journal of …, 2023 - mdpi.com
… could reverse oxidant stress and apoptosis of mouse oocytes in … , melatonin could attenuate
postovulatory oocyte dysfunction to delay oocyte aging by regulating SIRT1 expression [35]. …
postovulatory oocyte dysfunction to delay oocyte aging by regulating SIRT1 expression [35]. …
Melatonin as potential targets for delaying ovarian aging
Y Yang, HH Cheung, C Zhang, J Wu… - Current drug …, 2019 - ingentaconnect.com
… Melatonin is involved in immune regulation and may … Impairment of SIRT1 signaling is closely
related to oocyte … end products (RAGE) was attenuated by the melatonin [208], the receptor …
related to oocyte … end products (RAGE) was attenuated by the melatonin [208], the receptor …
[HTML][HTML] The effect of melatonin on mitochondrial function and autophagy in in vitro matured oocytes of aged mice
ZNH Almohammed, F Moghani-Ghoroghi… - Cell Journal …, 2020 - ncbi.nlm.nih.gov
… oocyte aneuploidy, and mitochondrial dysfunction in oocytes … Melatonin could increase the
SIRT1 expression in aged MII … that melatonin attenuated autophagy in postovulatory oocytes …
SIRT1 expression in aged MII … that melatonin attenuated autophagy in postovulatory oocytes …
[HTML][HTML] Research progress of melatonin (MT) in improving ovarian function: a review of the current status
YM Guo, TC Sun, HP Wang, X Chen - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
… may attenuate the age-related telomere shortening in oocytes [55]… the ovarian SIRT1 and
SIRT3 mRNA expression levels. … disorders of HPO axis in PCOS patients lead to the disorder of …
SIRT3 mRNA expression levels. … disorders of HPO axis in PCOS patients lead to the disorder of …
Aging-Related Ovarian Failure and Infertility: Melatonin to the Rescue
… (oocyte) which results in offspring with genetic disorders or in … docking and fertilization in
the post-ovulatory oocyte [91]. Lipid … telomeres and improved expression of SIRT1 and SIRT3 …
the post-ovulatory oocyte [91]. Lipid … telomeres and improved expression of SIRT1 and SIRT3 …
Fisetin Delays Postovulatory Oocyte Aging by Regulating Oxidative Stress and Mitochondrial Function through Sirt1 Pathway
X Xing, Y Liang, Y Li, Y Zhao, Y Zhang, Z Li, Z Li, Z Wu - Molecules, 2023 - mdpi.com
… dysfunction through the SIRT1 pathway during postovulatory aging. … We found that fisetin
regulated the expression of … also delayed postovulatory oocyte aging and attenuated the aging-…
regulated the expression of … also delayed postovulatory oocyte aging and attenuated the aging-…