SCM-198 ameliorates the quality of postovulatory and maternally aged oocytes by reducing oxidative stress

W Ma, X Zhao, Q Wang, X Wu, T Yang, Y Chen… - Journal of Ovarian …, 2024 - Springer
… For example, melatonin can regulate ovarian function … and spindle apparatus morphological
disorder, which could be … protein expression level of Juno in postovulatory aged oocytes

The close relationship between oocyte aging and telomere shortening, and possible interventions for telomere protection

S Ozturk - Mechanisms of Ageing and Development, 2024 - Elsevier
… Thus, reproductive and postovulatory aging lead to … that SAC dysfunction and cohesion
aberration in aging oocytes mostly … aging on oocytes may be prevented or attenuated by different …

The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review

M Samare-Najaf, A Neisy, A Samareh, D Moghadam… - Autophagy, 2023 - Taylor & Francis
… flux on the reproductive disorders including oligospermia, … Recently, the regulatory role
of Sirt1 on TST biosynthesis is … Melatonin, for example, could improve oocyte maturation …

Cumulus Cells Accelerate Postovulatory Oocyte Aging through IL1–IL1R1 Interaction in Mice

X Wen, Q Yang, D Sun, ZY Jiang, T Wang… - International Journal of …, 2023 - mdpi.com
… changes in the GSEA pathway to establish the core regulatoryexpression of RELA and
NFKB1 proteins in aging oocytes. … aging undergo mitochondrial dysfunction, abnormal …

Dihydromyricetin supplementation during in vitro culture improves porcine oocyte developmental competence by regulating oxidative stress

J Wang, QG Jin, RP Liu, XQ Wang, YH Li… - … of Reproduction and …, 2023 - jstage.jst.go.jp
… Adding antioxidants or hormones to the culture medium can prevent mitochondrial dysfunction
… , the mRNA expression levels of the antioxidant stress genes SOD1, SOD2, and SIRT1 in …

Advances in cytokine-based herbal medicine against premature ovarian insufficiency: A review

Y Siyu, Z Shixiao, S Congying, Z Xinqin, H Zhen… - Journal of …, 2024 - Elsevier
… the number and/or quality of oocytes in the ovaries before the age of … attenuating oxidative
stress and inflammatory responses and … by up-regulating PPAR-γ and SIRT1 expression. RES …

Melatonin, clock genes, and mammalian reproduction: what is the link?

A Brzezinski, S Rai, A Purohit… - International journal of …, 2021 - mdpi.com
… hormones leading to various reproductive disorders [40,41]. … Others [45] reported that the
clock genes BMAL1 and SIRT1 … are disrupted or attenuated in pathological reproductive …

An interplay between epigenetics and translation in oocyte maturation and embryo development: assisted reproduction perspective

M Dvoran, L Nemcova, J Kalous - Biomedicines, 2022 - mdpi.com
… that the SIRT1 anti-oxidative stress effect in mouse oocytes is … cellular damage leading to
the impairment of oocyte quality [235]. … damage by the attenuated expression of cytochrome c …

Quercetin protects porcine oocytes from in vitro aging by reducing oxidative stress and maintaining the mitochondrial functions

Y Jiao, Y Wang, T Jiang, K Wen, P Cong… - Frontiers in Cell and …, 2022 - frontiersin.org
… can alleviate post-ovulatory aging of mouse oocytes by … ROS accumulation can induce
mitochondrial dysfunction. … We found that attenuation of oxidative stress by QUE could …

Role of Melatonin in Ovarian Function. Animals 2024, 14, 644

G Basini, F Grasselli - 2024 - europepmc.org
… In fact, some studies suggest that melatonin regulates … can prevent the aging of the
porcine post-ovulatory oocyte … cell degeneration, impairment of the oocyte maturation process…