IL-10 as a Th2 cytokine: differences between mice and humans
MT Rasquinha, M Sur, N Lasrado… - The Journal of …, 2021 - journals.aai.org
… cross-regulation between Th1 and Th2 cytokines. Although … in a head-to-tail fashion with a
flexible linker, murine IL-10 (mIL-10… -IL-10 induced long-term CD8 + T cell memory, leading to …
flexible linker, murine IL-10 (mIL-10… -IL-10 induced long-term CD8 + T cell memory, leading to …
Epigenetic regulation of T cell memory: recalling therapeutic implications
DF Tough, I Rioja, LK Modis, RK Prinjha - Trends in immunology, 2020 - cell.com
… ability to express cytokines other than IL-2. The imprinting of … mechanisms that regulate gene
expression and review recent … Early work analyzing mouse T cells differentiated under Th1 …
expression and review recent … Early work analyzing mouse T cells differentiated under Th1 …
Role of Th1 and Th2 in autoimmunity
… Th1 T cell's main cytokines are IFN-γ, IL-2, and TNF-α, which can induce classical activation
… specificity, memory, and tolerance of self-antigens. The combination of these features allows …
… specificity, memory, and tolerance of self-antigens. The combination of these features allows …
[HTML][HTML] High-dimensional T helper cell profiling reveals a broad diversity of stably committed effector states and uncovers interlineage relationships
L Tortola, A Jacobs, L Pohlmeier, FJ Obermair… - Immunity, 2020 - cell.com
… responses established during primary antigen encounters in Th1- and Th2-cell-polarizing …
cytokine footprints of Th cells can be dynamic and change during an effector and memory …
cytokine footprints of Th cells can be dynamic and change during an effector and memory …
[HTML][HTML] Vitamin D and IFN-β modulate the inflammatory gene expression program of primary human T lymphocytes
… IFN-β on cytokine production and gene expression, we first … and IL-10 expression in different
human T cell subpopulations … the expression of this gene in treated and untreated memory T …
human T cell subpopulations … the expression of this gene in treated and untreated memory T …
Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+ T Cells
DA Kulpa, A Talla, JH Brehm, SP Ribeiro… - Journal of …, 2019 - Am Soc Microbiol
… Differential responses of memory CD4 + T cell subsets to … HIV gene expression is associated
with heightened expression … -inflammatory cytokines, such as TGF-β, also promote memory …
with heightened expression … -inflammatory cytokines, such as TGF-β, also promote memory …
Altered T cell plasticity favours Th17 cells in early arthritis
J Leipe, F Pirronello, H Schulze-Koops… - …, 2020 - academic.oup.com
… cytokines induce IL-17 expression in in vitro-generated Th1 … Th1 cells towards Th1/Th17
cells might imply that memory … commitment and control of gene expression, we also studied …
cells might imply that memory … commitment and control of gene expression, we also studied …
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes
A Hertweck, M Vila de Mucha, PR Barber… - Nucleic Acids …, 2022 - academic.oup.com
… gene encoding the T H 1 subtype-defining cytokine interferon gamma (IFNγ) and represses
genes encoding the T H 2 cytokines … or mTagBFP tag separated by a flexible glycine linker (…
genes encoding the T H 2 cytokines … or mTagBFP tag separated by a flexible glycine linker (…
Evolution of antigen-specific follicular helper T cell transcription from effector function to memory
AM Robinson, BW Higgins, AG Shuparski… - Science …, 2022 - science.org
… we looked at the differential gene expression across the TFH within … Because the persistent
TFH express a separable … We additionally saw GO enrichment of regulatory cytokine (TFGβ, Il-…
TFH express a separable … We additionally saw GO enrichment of regulatory cytokine (TFGβ, Il-…
Emergent dynamics of a three-node regulatory network explain phenotypic switching and heterogeneity: a case study of Th1/Th2/Th17 cell differentiation
… Different Th cells—Th1, Th2, and Th17 among others—have distinct cytokine and functional
… quantified the extent of changes in Th1, Th2, and Th17 signature gene-sets under diverse …
… quantified the extent of changes in Th1, Th2, and Th17 signature gene-sets under diverse …