Metabolomics in Preclinical Drug Safety Assessment: Current Status and Future Trends
… Metabolomics is emerging as a powerful systems biology approach for improving preclinical
… This review discusses current applications and future trends of metabolomics in toxicology …
… This review discusses current applications and future trends of metabolomics in toxicology …
Approaches in metabolomics for regulatory toxicology applications
… metabolomic studies with regulatory purposes 26 and performing relevant metabolomic … an
overview of the metabolomic workflow for regulatory toxicology purposes through the study of …
overview of the metabolomic workflow for regulatory toxicology purposes through the study of …
Metabolomics in pharmacology-a delve into the novel field of pharmacometabolomics
M Mussap, C Loddo, C Fanni… - Expert review of clinical …, 2020 - Taylor & Francis
… Short term toxicological studies on animal model conducted … preclinical toxicology tests
with molecular profiling technologies, such as transcriptomics, proteomics, and metabolomics for …
with molecular profiling technologies, such as transcriptomics, proteomics, and metabolomics for …
Metabolomics as a truly translational tool for precision medicine
JC Schmidt, BV Dougherty, RD Beger… - … journal of toxicology, 2021 - journals.sagepub.com
… Thus, metabolomics is more than a promise of the future; metabolomics is already available
… This ACT Symposium review will contain an introduction to metabolomics in toxicity studies …
… This ACT Symposium review will contain an introduction to metabolomics in toxicity studies …
Use cases, best practice and reporting standards for metabolomics in regulatory toxicology
MR Viant, TMD Ebbels, RD Beger, DR Ekman… - Nature …, 2019 - nature.com
… The MEtabolomics standaRds Initiative in Toxicology (MERIT… applications for metabolomics
in regulatory toxicology and … acquiring and analysing untargeted metabolomics and targeted …
in regulatory toxicology and … acquiring and analysing untargeted metabolomics and targeted …
The use of animal models in metabolomics
JL Griffin - Metabolomics for Biomedical Research, 2020 - Elsevier
… A schematic representation for preclinical screening in drug toxicity tests. … metabolomics
has a good track record in 3R initiatives, particularly in the use of biofluid analysis in toxicology …
has a good track record in 3R initiatives, particularly in the use of biofluid analysis in toxicology …
[PDF][PDF] Metabolomics in Preclinical Drug Safety Assessment: Current Status and Future Trends. Metabolites 2024, 14, 98
… This review discusses current applications and future trends of metabolomics in toxicology …
of metabolomics in toxicology and discusses its future trends, focusing on its role in preclinical …
of metabolomics in toxicology and discusses its future trends, focusing on its role in preclinical …
[PDF][PDF] Advancing The Applications of In vitro Metabolomics in Toxicology
S Ramirez Hincapie - 2023 - kluedo.ub.rptu.de
… of metabolomics in toxicology, this work has significantly contributed to the aim of toxicology
… relevant non-animal toxicological testing, supporting the toxicology task of protecting human …
… relevant non-animal toxicological testing, supporting the toxicology task of protecting human …
Confidence in metabolite identification dictates the applicability of metabolomics to regulatory toxicology
JM Malinowska, MR Viant - Current Opinion in Toxicology, 2019 - Elsevier
… immediately be evident that this represents a potentially serious impediment to the application
of metabolomics data to regulatory toxicology, which we explore in the following sections. …
of metabolomics data to regulatory toxicology, which we explore in the following sections. …
The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics
… This has been classically examined in the early preclinical … the use of animals for toxicological
research, without compromising its … Toxicology assessments through in vitro metabolomic …
research, without compromising its … Toxicology assessments through in vitro metabolomic …