… use of metal chelating agents may be a viable method for ameliorating Alzheimer’s Disease
pathology, as its etiology remains obscure. We conclude that, although metal therapies can …

… Manganese is an essential trace metal required for normal … Understanding the roles of these
heavy metals in the etiology of … metals in this review because neurotoxicity of these metals is …

… of redox metals in biology (biomimetic oxidations, mechanism of action of peroxide based
antimalarial drugs) and redox metal homeostasis for chemotherapy of Alzheimer’s disease. …

… The homeostasis of metal ions, such as iron, copper, zinc and calcium, in the brain is crucial
… metal ions in the brain is closely related to the onset and progression of Alzheimer’s disease …

… mentioned metal imbalance in … metals, but rather to a more initial distribution of intracellular
ions in an unclear manner. Therefore, brain metal homeostasis is regulated by several metal …

… metal homeostasis at the cellular and organismal levels. Herein, we review how these metals
… of toxicity by which metals can contribute to AD. Our goal is to increase the awareness of …

… Abstract: Alzheimer’s disease (AD) is one of the life-… ), loss of mitochondrial function, altered
metal homeostasis, aberrant … , the role of some important metals in the progression of AD and …

… metals in AD and discusses the advances in chelation strategies and developments adopted
in the treatment of the disease… and zinc (Zn)) and metal-amyloid interactions that lead to the …

… with abnormal levels or overload of brain metals. Recent Advances: Several promising
compounds targeting oxidative stress, redox metals, and neuronal death are under preclinical or …

… Therefore, the metal ion chelators were recognized as … This review comprehensively
summarized the effects of metal … metal ions on neuroinflammation and highlighted the metal ion …