Protective effects of melatonin on methamphetamine-induced bloodbrain barrier dysfunction in rat model

J Namyen, K Permpoonputtana, C Nopparat… - Neurotoxicity …, 2020 - Springer
… The results showed a significantly increased hippocampal expression of albumin (P < 0.05;
Fig. 1(m)) induced by METH as compared to control groups. This effect could be protected by …

[HTML][HTML] Overview of blood-brain barrier dysfunction in methamphetamine abuse

L Pang, Y Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… This study demonstrated that chronic METH increased α-syn expression in mice hippocampal
neurons [68]. The α-syn produced by neurons were spread to astrocytes and gradually …

The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties

TP Buzhdygan, CR Rodrigues, HM McGary… - Journal of …, 2021 - Springer
Methamphetamine, which closely resembles chemical structure and pharmacological …
Here, we report that extracellular PECAM-1 was transiently increased in hBMVEC at 2 h after …

Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier

JH Chang, C Greene, K Frudd, LA Dos Santos… - Cell Reports …, 2022 - cell.com
… The blood-brain barrier (BBB) restricts clinically relevant accumulation of many …
Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: …

[HTML][HTML] Effect of Endurance Exercise and Methamphetamine Administration on the Expression of Blood-Brain Barrier Related Factors and BDNF in Hippocampus of …

SR Jung - Exercise Science, 2022 - ksep-es.org
… This study aimed to investigate the effect of short-term endurance exercise and
methamphetamine administration on bloodbrain barrier (BBB)-related marker and brain-derived …

Methamphetamine induces systemic inflammation and anxiety: the role of the gut–immune–brain axis

M Davidson, M Mayer, A Habib, N Rashidi… - International journal of …, 2022 - mdpi.com
… ) and cross the bloodbrain barrier (BBB), inducing an inflammatory response within the …
Immunohistochemistry analysis of brain hippocampus tissues showed an increase in albumin …

GKT136901 protects primary human brain microvascular endothelial cells against methamphetamine-induced blood-brain barrier dysfunction

JS Hwang, EH Cha, E Ha, B Park, JH Seo - Life Sciences, 2020 - Elsevier
… It has been well established that METH induces irreversible damage of dopaminergic
neurons in certain brain regions, including striatum, hippocampus, and cortex [1,2]. Thus, …

Methamphetamine enhances caveolar transport of therapeutic drugs across the rodent blood-brain barrier

JH Chang, C Greene, C Futter, BJ Nichols, M Campbell… - bioRxiv, 2020 - biorxiv.org
… Low dose methamphetamine (METH) induces fluid phase transcytosis across the BBB …
Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus

Protective effect of neuropeptide Y2 receptor activation against methamphetamine-induced brain endothelial cell alterations

F Ventura, M Muga, V Coelho-Santos… - Toxicology Letters, 2020 - Elsevier
Methamphetamine (METH) consumption is a health problem that leads to neurological and
… Although promising advances in understanding the blood-brain barrier (BBB) alterations …

Effect of chronic methylphenidate treatment on hippocampal neurovascular unit and memory performance in late adolescent rats

V Coelho-Santos, FL Cardoso, A Magalhães… - European …, 2019 - Elsevier
… dose of MPH caused hippocampal blood-brain barrier (BBB) … use, such as cocaine and
methamphetamine, are often … HBMVECs at about 70% confluence were transiently transfected …