Microfluidic devices for imaging and manipulation of C. elegans

AS Clark, J Huayta, KS Arulalan… - Micro and Nano Systems …, 2021 - Elsevier
microfluidic approaches that have emerged to improve the control and throughput of the
imaging and manipulation of C… into microfluidic technologies aimed at improve screening and …

Microfluidic approaches for Caenorhabditis elegans research

E Levine, KS Lee - Animal cells and systems, 2020 - Taylor & Francis
… layer for microfluidic devices is manufactured using a mold … of individual worms to another
imaging platform, such as an … in a microfluidic device enable in situ high-resolution imaging

Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans

D Midkiff, A San-Miguel - Molecules, 2019 - mdpi.com
… screens that involve high-resolution imaging is the microfluidic tapered channel (Figure 1a).
This … of labs that commit to using LOC technology find microfluidic methods to be much more …

Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform

H Baris Atakan, T Alkanat, M Cornaglia… - Microsystems & …, 2020 - nature.com
… embryo phenotyping microfluidic approach to observe C. … extracted using CNN—we provided
three types of image patches … We fabricated our microfluidic chips by soft lithography using

Caenorhabditis elegans-on-a-chip: microfluidic platforms for high-resolution imaging and phenotyping

S Mondal, A Ben-Yakar - Organ-on-a-chip, 2020 - Elsevier
… describes microfluidics-based platforms for screening C. … Microfluidics is the science of
using the forces generated by … showing approaches for immobilizing Caenorhabditis elegans

High-Content and High-Throughput In Vivo Drug Screening Platforms Using Microfluidics

A Ben-Yakar - Assay and drug development technologies, 2019 - liebertpub.com
screening methods based on in vivo small animal models such as Caenorhabditis elegans,
… technologies20,21,24–27 as well as ultrafast imaging methods,28 pushing the technological …

Advances in C. áelegans behavior research with microfluidic devices and its future prospects in the evaluation of exogenous pollutants

X Zhang, J Sun, X Yuan, X Lu, X Sun - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
… The nematode Caenorhabditis elegans (C.áelegans) is characterized by small size, a …
how to manipulate nematodes with microfluidic devices, such as immobilization, imaging, …

[PDF][PDF] Microfluidic-based imaging of complete Caenorhabditis elegans larval development

S Berger, S Spiri, A DeMello, A Hajnal - Development, 2021 - journals.biologists.com
… In recent years, a number of microfluidic approaches for C. elegans imaging have been …
Using our L1 device, we were able to image worms loaded immediately after hatching and until …

Multimodal imaging and high-throughput image-processing for drug screening on living organisms on-chip

D Migliozzi, M Cornaglia, L Mouchiroud… - … of biomedical optics, 2019 - spiedigitallibrary.org
… information that is missing when using cellular models. Caenorhabditis elegans is a soil worm
… how multimodal imaging on a well-designed microfluidic chip for multiplexed analysis on …

Studying Parkinson's disease using Caenorhabditis elegans models in microfluidic devices

K Youssef, A Tandon, P Rezai - Integrative Biology, 2019 - academic.oup.com
elegans for toxicology and drug screening in PD is also of … elegans-based conventional
and microfluidic approaches to … allows direct imaging of neurons and protein expression using