[HTML][HTML] Microneedles: A potential strategy in transdermal delivery and application in the management of psoriasis

Z Zhao, Y Chen, Y Shi - Rsc Advances, 2020 - pubs.rsc.org
… Every type of these microneedles has different advantages according to their … microneedles,
the progress of the microneedle application in the management of psoriasis and the clinical

Clinical testing of microneedles for transdermal drug delivery

RK Sivamani, GC Wu, H Zhai, HI Maibach… - Percutaneous …, 2021 - taylorfrancis.com
… of microneedle technology. In fact, two pilot clinical studies have evaluated the use of
microneedle-… In both studies microneedles that were shorter than 700 microns were used and …

Comprehensive evaluation of microneedle‐based intradermal adalimumab delivery vs. subcutaneous administration: results of a randomized controlled clinical trial

J Jacobse, W Ten Voorde, A Tandon… - … journal of clinical …, 2021 - Wiley Online Library
… The commercially available microneedles used in the clinical trial reported in this paper have
been used in various clinical studies. Each device consists of 3 hollow microneedles with a …

[HTML][HTML] Microneedle-based delivery: An overview of current applications and trends

AJ Guillot, AS Cordeiro, RF Donnelly, MC Montesinos… - Pharmaceutics, 2020 - mdpi.com
… ensuring the sterility of the MNA vaccines for clinical applications. Van der Maadden et al.
developed hollow microneedles manufactured with hydrofluoric acid fused silica capillaries for …

Prospection of fabrication techniques and material selection of microneedles for transdermal drug delivery: An update on clinical trials

NR Naveen, PS Goudanavar, B Ramesh… - Materials Today …, 2022 - Elsevier
… to design several microneedle geometries. Various approaches to microneedle delivery of
drugs (… Following a brief introduction to microneedle for transdermal application, this review …

Microneedles for extended transdermal therapeutics: a route to advanced healthcare

S Pahal, K Badnikar, V Ghate, U Bhutani… - European Journal of …, 2021 - Elsevier
… triggers to different microneedle-based devices for on-… microneedle-based devices for
sustained release of vaccines, hormones, and antiretrovirals with their prospective safe clinical

[HTML][HTML] A systematic review of carbohydrate-based microneedles: Current status and future prospects

RS Bhadale, VY Londhe - Journal of Materials Science: Materials in …, 2021 - Springer
… a few accomplished positive clinical testing results. Table 6 summarizes active and completed
clinical trials using carbohydrate-based microneedles [91]. Since microneedles are novel …

[HTML][HTML] Recent advances in microneedles-mediated transdermal delivery of protein and peptide drugs

T Liu, M Chen, J Fu, Y Sun, C Lu, G Quan, X Pan… - … Pharmaceutica Sinica B, 2021 - Elsevier
clinical administration of protein and peptide drugs, which usually leads to poor patient's
compliance. As a portable, minimally invasive device, microneedles … status of clinical translation …

Exploiting unique features of microneedles to modulate immunity

C Edwards, SA Shah, T Gebhardt… - Advanced …, 2023 - Wiley Online Library
… We examine pre-clinical studies showing MNAs maintain or improve disease outcomes
compared to traditional injection routes., then discuss how distinct formulation and …

Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024 - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging from
… Finally, we provide a survey on clinical applications of MNs and discuss opportunities and …