… visceral pain 24 and the activation of microglia and astrocytes … found that minocycline could
attenuate pain and depressive-… induced by spinal nerve ligation by its inhibitory effects on the …

… The inhibition of spinal P2X7R with BBG could effectively inhibit BCP due to suppressing the
expression of NF-κB p… Chanling Gao attenuates bone cancer pain in rats by the IKKbeta/NF-…

… attenuated mechanical allodynia in bone cancer pain rats, … edema, and inhibited NF-κB
activation and downregulated the … and astrocytes, originated from the spinal cords of neonatal rats…

… regulated the proliferation of spinal astrocytes in a rat model of neuropathic pain. However,
… of intrathecal delivery of minocycline to attenuate pain behaviour in BCP rats. Minocycline (4, …

… and the underlying mechanisms within the spinal cord (SC) and … mass and attenuates pain
behaviors in the BCP model rats. … also reported that activated NF-κB (p-NF-κB) modulated the …

… h) in rat spinal cord slices (Pinkernelle et al., 2013). A high dose of minocycline attenuated
… Some previous studies demonstrate that IκBz can serve as a nuclear inhibitor of NF-κB and …

… that the spinal NF-κB/p65 pathway in astrocytes modulates … addition, minocycline significantly
reverses bone cancer pain-… delivered NF-κB/p65 inhibitor PDTC obviously attenuated …

… spinal cord level, JNK upregulation is observed in astrocytes … literature indicates that the
inhibition of NF-κB may directly or … treatment with LY294002 attenuates hypersensitivity in rats …

… The effects of CGRP and minocycline treatment on … have demonstrated that CGRP acts
through inhibiting the NF-κB … inhibit microglial activation in the spinal cord in DLBP rats. Our 484 …

… spinal neurons and astrocytes to promote central sensitization and chronic … that minocycline,
a non-selective inhibitor of microglia, attenuated neuropathic pain; however, minocycline is …