… study by exploring the modulation of CUMS on the pathway of the CORT--microglial M1/M2--…
that CUMS and minocycline significantly influenced the mRNA expression of CD11b (χ 2 (3) …

… -related gene expression changes that are modulated by … cortex are paralleled by pain
responses in different animal models of … microglia activity in CCI-induced neuropathic pain rats. …

… cortex following nerve injury 25 suggested a role of brain … We noted that the M1 microglia
phenotype dominated in the … initiation stage of neuropathic pain, minocycline’s pain-relieving …

… the thalamus and finally the cerebral cortex. (3) Perception: this … At the level of spinal cord,
microglia activation is modulated … bone cancer pain, while minocycline can mitigate the pain of …

… minocycline (1 μg, 30 min) prolonged the SCS-induced pain … of spinal glial cells in neuropathic
pain are still unknown. By … more effective modulation of gene expression and biological …

… directly added primary cortical microglia to co… minocycline can attenuate neuropathic pain
behavior in a rat model of depression via modulating the gene expression of M1-M2 microglial […

… that minocycline selectively inhibits the polarization of microglia … increased proportion of M1/
M2 in spinal cord microglia, and … treat neuropathic pain by restoring the proportion of M1/M2 …

… These studies have shown gene expression profiles that differ … low selectivity of minocycline
for the microglial phenotypes … the microglia transcriptome from human and mouse cortex and …

… In addition, a global gene expression profiling of spinal cord … mediators with minocycline
attenuated pain hypersensitivity … microglia and subsequently modulate the ascending pain …

… of behavioural changes characteristic of neuropathic pain. … to 120 minutes postinjection of
minocycline (100 µg) intrathecal … (D) The mRNA expression of Bdnf (normalized to Gapdh) in …