Minority and majority pretreatment HIV-1 drug resistance associated with failure of first-line nonnucleoside reverse-transcriptase inhibitor antiretroviral therapy in …

RS Milne, RA Silverman, IA Beck, J Mckernan-Mullin… - Aids, 2019 - journals.lww.com
… Next-generation sequencing confirmed 25 of 26 (96.2%) drug resistance mutations … to draw
statistical conclusions, antiretroviral-naive women with minority variants in our study did not …

[HTML][HTML] Incidence and types of HIV-1 drug resistance mutation among patients failing first-line antiretroviral therapy

X Luo, G Su, J Huang, J Wu, H Su, W Huang… - Journal of …, 2019 - Elsevier
… of tropics and subtropics with minority (including Zhuang and … of HIV-1 subtype and
prevalence of HIV-1 drug resistance in … of HIV-1 drug resistance mutations in antiretroviral-naive

Low-abundance drug-resistant HIV-1 variants in antiretroviral drug-naive individuals: a systematic review of detection methods, prevalence, and clinical impact

HA Mbunkah, S Bertagnolio, RL Hamers… - The Journal of …, 2020 - academic.oup.com
… Since its introduction, antiretroviral therapy (ART) has greatly reduced global mortality rates
… were: “HIV drug resistance,” “minority variants,” “minority mutations,” “minority quasispecies,” …

HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis

F Ouyang, D Yuan, W Zhai, S Liu, Y Zhou, H Yang - Viruses, 2024 - mdpi.com
… However, other INSTI-associated resistance mutations were mainly minority variants which
… had received prior antiretroviral therapy (ART) in order to isolate the incidence of primary …

Diversity of HIV-1 subtypes and transmitted drug-resistance mutations among minority HIV-1 variants in a Turkish cohort

RC Sarinoglu, U Sili, U Hasdemir, B Aksu… - Current HIV …, 2022 - ingentaconnect.com
… 44 antiretroviral treatment-naïve patients. … drug resistance mutations (DRMs) in as low as
1 % of the viral population [38-42]. In this study, we aimed to determine the distribution of HIV-1

Genetic landscape for majority and minority HIV-1 drug resistance mutations in antiretroviral therapy naive patients in Accra, Ghana

P Appiah, G Gbassana, M Adusei-Poku, BM Obeng… - Heliyon, 2024 - cell.com
… is predicted to be useful for efficiently testing minority drug resistance mutations, which could
… compare minority and majority drug resistance mutations in HIV-1 strains in treatment-naive

Drug resistance to HIV-1 integrase inhibitors among treatment-naive patients in Beijing, China

F Yu, Q Li, L Wang, H Zhao, H Wu, S Yang… - Pharmacogenomics …, 2022 - Taylor & Francis
… quantitative identification of minority resistant variants (MRVs). … of NGS technology on TDR
mutations of INSTIs. Therefore, … mutations started NNRTI-based antiretroviral therapy and …

Prevalence and determinants of virological failure, genetic diversity and drug resistance among people living with HIV in a minority area in China: a population-based …

D Yuan, M Liu, P Jia, Y Li, Y Huang, L Ye, L Api… - BMC infectious …, 2020 - Springer
… , HIV-1 subtypes, and drug resistance to understand HIV-1 … the number of antiretroviral-naive
patients and reducing their … antiretroviral treatment, but also results in the spread of drug-…

Prevalence of drug resistance mutations among ART-naive and-experienced HIV-infected patients in Sierra Leone

GA Yendewa, F Sahr, S Lakoh, M Ruiz… - … of Antimicrobial …, 2019 - academic.oup.com
… The majority of our study participants were infected with the recombinant HIV-1 subtype
CRF02_AG (83.1%), with other minority variants making up <17.0%. These findings are in …

New antiretroviral inhibitors and HIV-1 drug resistance: more focus on 90% HIV-1 isolates?

E Ndashimye, PS Reyes, EJ Arts - FEMS Microbiology Reviews, 2023 - academic.oup.com
… still emerged, better outcomes in antiretroviral therapy-naïve PLWH were recorded with dual
Minority species of K103N or Y181C mutant viruses detected by ultrasensitive PCR were …