Hexokinase 2 displacement from mitochondriaassociated membranes prompts Ca2+‐dependent death of cancer cells

F Ciscato, R Filadi, I Masgras, M Pizzi, O Marin… - EMBO …, 2020 - embopress.org
… MAMs are dynamic structures that control the exchange between ER and mitochondria of …
autophagy, cell death and maintenance of glucose homeostasis 21-23. A pivotal role of MAMs …

How do hexokinases inhibit receptor-mediated apoptosis?

A Schoeniger, P Wolf, F Edlich - Biology, 2022 - mdpi.com
… Effects similar to the hexokinase II knockdown have been … and ER (mitochondria-associated
membranes; MAMs) by … tumors, hexokinase II is likely involved in cell death regulation. …

The hexokinase “HKDC1” interaction with the mitochondria is essential for liver cancer progression

MW Khan, AR Terry, M Priyadarshini, V Ilievski… - Cell death & …, 2022 - nature.com
… These data suggest that HKDC1 plays a pivotal role in LC progression, possibly via its …
hexokinase, HKDC1, by interacting with the mitochondria plays previously unidentified roles

Hexokinase 2 in cancer: a prima donna playing multiple characters

F Ciscato, L Ferrone, I Masgras, C Laquatra… - International journal of …, 2021 - mdpi.com
… it performs additional functions in autophagy regulation and cell death inhibition that are …
reticulum called Mitochondria Associated Membranes (MAMs) has unveiled a novel HK2 role in …

[HTML][HTML] PGAM5: a crucial role in mitochondrial dynamics and programmed cell death

M Cheng, N Lin, D Dong, J Ma, J Su, L Sun - European journal of cell …, 2021 - Elsevier
… activate mitochondrial dynamics to maintain normal functions, and an imbalance in
mitochondrial dynamics triggers multiple programmed cell death processes. Recent studies have …

Salicylic acid-induced ROS production by mitochondrial electron transport chain depends on the activity of mitochondrial hexokinases in tomato (Solanum …

P Poór, G Patyi, Z Takács, A Szekeres, N Bódi… - Journal of plant …, 2019 - Springer
cell death execution in plant tissues. The aim of this work was to study the putative role of
hexokinases (HXKs) in the initiation of cell death … the initiation of programmed cell death (PCD) …

The multifaceted roles of mitochondria at the crossroads of cell life and death in cancer

F Fontana, P Limonta - Free Radical Biology and Medicine, 2021 - Elsevier
play a pivotal role in several cellularmitochondria-associated membranes); this
mitochondria-ER communication supports the key functions of the two organelles in regulating cell

Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

K Seiler, M Humbert, P Minder, I Mashimo… - Cell death & …, 2022 - nature.com
… RNA sequencing analysis confirmed pathway enrichment for programmed cell death,
oxidative stress, and DNA damage response in HK3-null AML cells. These signatures were …

Sucrose treatment suppresses programmed cell death in broccoli florets by improving mitochondrial physiological properties

A Han, S Cao, Y Li, H Wang, Y Wei, X Shao… - Postharvest biology and …, 2019 - Elsevier
… The results showed that sucrose treatment effectively retarded the onset of programmed
cell death (PCD) in broccoli florets by a mitochondria-dependent pathway. Sucrose treatment …

… of life and death: changes in mitochondrial and cytosolic proteomes associated with programmed cell death of Arabidopsis thaliana suspension culture cells

J Schwarze, JC Carolan, GS Stewart… - Frontiers in Plant …, 2023 - frontiersin.org
Frontiers | The boundary of life and death: changes in mitochondrial and cytosolic proteomes
associated with programmed cell death of Arabidopsis thaliana suspension culture cells