… Moreover, mitochondria-derived ROS hold also a relevant … driving the secretion of mature
cytokines and pyroptosis, a … of pro-inflammatory cytokines such as several interleukins (IL-6, IL-…

… At the same time, ROS are important intracellular mediators that drive the appropriate … leads
to the secretion of proinflammatory cytokines, including IL-1β, TNFα, and IL-6 [18]. Therefore, …

… RORγt that drive differentiation and proinflammatory responses… that mitochondrial-derived
reactive oxygen species (ROS) … of SOD3 suppressed proinflammatory cytokine production and …

… activation, ROS generation and proinflammatory cytokine production in hepatic infiltrating …
mitochondrial ROS in macrophages. The signaling and damaging properties of ROS can drive …

… macrophages that drive the pro-inflammatory response [129], … by high glucose and pro-inflammatory
cytokines led to PTP … several mitochondrial processes, including ROS production …

… roles of mitochondrial reactive oxygen species (mtROS) … drives aerobic glycolysis and
reactive oxygen species (ROS) … of mtROS and proinflammatory cytokine expression with NLRP3 …

Significance: Mitochondria represent a major source of intracellular reactive oxygen species …
This is often a consequence of oxidative phosphorylation, which can produce ROS as a …

… and for the production of reactive oxygen species (ROS) upon pro-inflammatory activation.
Mfn2 deficiency specifically impairs the production of pro-inflammatory cytokines and nitric …

… causes the production of lipotoxins that induce mitochondrial … These pro-inflammatory cytokines
are well known to … one of the hallmark pathophysiological risk factors driving the disease, …

… drives IL-1β production and other proinflammatory cytokines by phagocytic and nonphagocytic
cells at the site of injury during IAV infection. This acute cytokine … the mitochondria have …